On April 11, 2018 Cellectis (Euronext Growth: ALCLS – Nasdaq: CLLS), a clinical-stage biopharmaceutical company focused on developing immunotherapies based on gene-edited allogeneic CAR T-cells (UCART), reported that three posters regarding the Company’s allogeneic, off-the-shelf, CAR-T product candidates will be presented at the American Association for Cancer Research (AACR) (Free AACR Whitepaper) Annual Meeting to be held from April 14 to 18, 2018, in Chicago, Illinois (Press release, Cellectis, APR 11, 2018, View Source [SID1234525258]).
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April 16, 2018, 8:00 AM – 12:00 PM Central Time
Section 45
Repurposing endogenous immune pathways to improve chimeric antigen receptor T-cells potency
M. Sachdeva1, B. Busser1, S. Temburni1, A. Juillerat1, L. Poirot2, P. Duchateau2, J. Valton1;
1Cellectis, New York, NY, 2Cellectis, Paris, France
April 16, 2018, 1:00 PM – 5:00 PM Central Time
Section 24
Preclinical efficacy of allogeneic anti-CD123 CAR T-cells for the therapy of blastic plasmacytoid dendritic cell neoplasm (BPDCN)
T. Cai1, K. L. Black2, A. Naqvi2, R. Galetto3, A. Gouble3, J. Smith4, A. Cavazos1, L. Han1, Q. Zhang1, V. Kuruvilla1, S. N. Sergej Konoplev1, S. S. Neelapu1, A. A. Lane5, M. L. Guzman6, H. Kantarjian1, A. Thomas-Tikhonenko2, N. Pemmaraju1, M. Konopleva1;
1UT MD Anderson Cancer Ctr., Houston, TX, 2The Children’s Hosp. of Philadelphia, Philadelphia, PA, 3Cellectis SA, Paris, France, 4Cellectis Inc, New York, NY, 5Dana-Farber Cancer Inst., Boston, MA, 6Weill Cornell Med. Coll., New York, NY
April 18, 2018, 8:00 AM – 12:00 PM Central Time
Section 31
Prediction of immunotherapy outcome by multimodal assessment of minimal residual disease and persistence of allogeneic anti-CD123 CAR T-cells (UCART123) in pre-clinical models of acute myeloid leukemia
M. Sugita1, N. Mencia-Trinchant1, N. Ewing-Crystal1, G. Suppa1, R. Galetto2, A. Gouble2, J. Smith3, G. J. Roboz1, D. C. Hassane1, M. L. Guzman1;
1Weill Cornell Med., New York, NY, 2Cellectis SA, Paris, France, 3Cellectis Inc, New York, NY
Abstracts are available on the AACR (Free AACR Whitepaper) website. The three posters to be presented at the 2018 AACR (Free AACR Whitepaper) Annual Meeting will be available on the Cellectis website after April 18, 2018.