On May 21, 2003 Cancer Research Technology Ltd. (CRT), the technology transfer arm of the charity Cancer Research UK, and the University of Newcastle, both based in the UK, reported to recently disclose that a new alliance with the US and UK-based biotechnology company OSI Pharmaceuticals (UK) had recently commenced and was expected to accelerate the validation of certain new targets for cancer therapeutic intervention (Press release, Cancer Research Technology, MAY 21, 2003, View Source [SID1234523463]).

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This exciting collaboration will enable the development of selective and potent modulators of protein acetylation and evaluate their potential as inhibitors of tumour cell growth. Furthermore, the co-funded research programme may also enable the discovery and validation of other targets against which new drugs can be screened in the fight against cancer.

The research funding that had enabled developments in this field at the University of Newcastle to progress to this stage predominantly stemmed from Cancer Research UK who are continuing to support the programme. CRT was happy to act on Cancer Research UK’s behalf to secure the fast track development of this exciting work regarding the potential discovery of new compounds with a partner who has a proven track record of taking such compounds that act on new cancer-specific signal transduction pathways in to the clinic.

Such a collaboration may help scientists to understand why certain cancer patients become resistant to currently available therapies.