On January 4, 2023 bioAffinity Technologies, Inc. (NASDAQ: BIAF; BIAFW) reported that the U.S. Patent and Trademark Office (USPTO) has provided a Notice of Allowance for a patent application titled "Porphyrin Compounds and Compositions Useful for Treating Cancer" for the targeted delivery of novel cancer treatments (Press release, BioAffinity Technologies, JAN 4, 2023, View Source [SID1234625789]). A Notice of Allowance is issued after the USPTO makes a determination that a patent should be granted for the claimed invention. The U.S. patent will issue to the Company’s wholly owned subsidiary OncoSelect and grant protection to 2037.
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"A little more than 1.9 million new cancer cases are expected to have been diagnosed in the United States in 2022," said Maria Zannes, President and Chief Executive Officer of bioAffinity Technologies. "Not surprisingly, the cost of cancer is staggering. National expenditures for cancer care in the United States in 2018 were $150.8 billion. The larger cost is borne by patients who undergo therapies that often lead to toxic treatment-associated side effects. New treatments delivered by more specific targeting agents like porphyrins are needed to improve survival and a survivor’s quality of life. bioAffinity Technologies is committed to bringing these treatments to market."
Research related to the Company’s non-invasive lung cancer diagnostic CyPath Lung led to the discoveries being developed to treat cancer including using porphyrins conjugated with oncological drugs for more targeted delivery with fewer unwanted treatment-associated side effects. Porphyrins, such as the synthetic molecule TCPP used in CyPath Lung, preferentially enter cancer cells and may lead to greater uptake of chemotherapeutics attached to the porphyrin with less impact on healthy cells.
"The selectivity of porphyrins that preferentially bind with cancer cells makes them excellent candidates for drug delivery and diagnostic products," said Dr. William Bauta, bioAffinity Technologies’ Senior Vice President of Therapeutics. "Selective delivery of drugs that kill cancer with little harm to healthy cells helps patients tolerate therapy, leading to more effective treatment that saves lives."
bioAffinity Technologies is advancing its therapeutic assets with the intent to license its products for clinical development. Its subsidiary OncoSelect holds patents to Porphyrin Compounds and Compositions Useful for Treating Cancer in Australia, China and Mexico and pending applications in Canada, the European Patent Office, Hong Kong, India and Japan.