On February 6, 2023 Arvinas, Inc. (Nasdaq: ARVN), a clinical-stage biotechnology company creating a new class of drugs based on targeted protein degradation, reported that management will participate in three upcoming investor conferences (Press release, Arvinas, FEB 6, 2023, View Source [SID1234626857]):

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Guggenheim Oncology Conference on Thursday, February 9. Ron Peck, M.D., Chief Medical Officer, and Sean Cassidy, Chief Financial Officer, will participate in a fireside chat. A live audio webcast of the presentation will be available here and on the Events + Presentations section of the Company’s website.

SVB Leerink Global Healthcare Conference on Thursday, February 16. Ron Peck, M.D., Chief Medical Officer, and Randy Teel, Ph.D., Senior Vice President, Corporate and Business Development, will participate in a fireside chat. A live audio webcast of the presentation will be available here and on the Events + Presentations section of the Company’s website.

Citi Oncology Leadership Summit on Thursday, February 23. Ian Taylor, Ph.D., Chief Scientific Officer, will participate in a fireside chat. A live audio webcast of the presentation will be available here and on the Events + Presentations section of the Company’s website.

On February 6, 2023 Arbutus Biopharma Corporation (Nasdaq: ABUS), a clinical-stage biopharmaceutical company leveraging its extensive virology expertise to develop novel therapeutics that target specific viral diseases, reported that the Arbutus management team will participate in and host one-on-one meetings at the following three upcoming investor conferences (Press release, Arbutus Biopharma, FEB 6, 2023, View Source [SID1234626856]):

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SVB Securities Global Biopharma Conference – Virtual: February 14-16, 2023

Cowen 43rd Annual Health Care Conference: Formal Presentation at 1:30 pm ET on March 7, 2023

Jefferies Biotech on the Bay Summit: March 16-17, 2023

To access the live webcast of the presentation for the Cowen 43rd Annual Health Care Conference please visit: View Source An archived replay of the webcast will be available on the Arbutus website for a limited time after the event.

On February 6, 2023 Akoya Biosciences, Inc. (Nasdaq: AKYA) ("Akoya"), The Spatial Biology Company, reported that it will release financial results for the fourth quarter and full year of 2022 after the market close on Monday, March 6th, 2023 (Press release, Akoya Biosciences, FEB 6, 2023, View Source [SID1234626855]). Company management will host a conference call to discuss financial results at 5:00 p.m. ET.

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Investors interested in listening to the conference call are required to register online. It is recommended to register at least a day in advance. A live and archived webcast of the event will be available on the "Investors" section of the Akoya website at View Source

Akoya also announced that Brian McKelligon, CEO, will be participating in two upcoming investor conferences.

BTIG MedTech, Digital Health, Life Science & Diagnostic Tools Conference

43rd Annual Cowen Healthcare Conference
Tuesday, March 7th at 2:10 p.m. ET
A live webcast of the 43rd Annual Cowen Healthcare Conference will be available on the "Investors" section of the Akoya website View Source

On February 6, 2023 Aim Immunotech presented its investor presentation (Presentation, AIM ImmunoTech, FEB 6, 2023, View Source [SID1234626854]).

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On February 6, 2023 Immutep Limited (ASX: IMM; NASDAQ: IMMP) ("Immutep" or "the Company"), a clinical-stage biotechnology company developing novel LAG-3 immunotherapies for cancer and autoimmune diseases, reported the investigator-initiated INSIGHT-003 trial has reached its enrolment target of 20 patients with 1L NSCLC (Press release, Immutep, FEB 6, 2023, View Source [SID1234626839]). INSIGHT-003 is the first trial evaluating Immutep’s lead product candidate, eftilagimod alpha ("efti" or "IMP321") as part of a triple combination therapy with standard-of-care anti-PD-1 therapy and chemotherapy.

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Immutep’s CSO & CMO Dr Frederic Triebel said, "The promising initial efficacy and favourable safety results reported in November 2022 from this first triple combination approach instils more confidence in the flexibility of our novel immunotherapy, efti to be combined with various therapeutics and safely drive superior patient outcomes. We are pleased to have reached our enrolment target and look forward to reporting as the results mature further. Additional data from INSIGHT-003 will help further inform our next steps in 1 st line NSCLC."

In a poster presented at the Society for Immunotherapy of Cancer (SITC) (Free SITC Whitepaper) Annual Meeting 2022, initial results in 1L NSCLC patients show the triple combination therapy is well-tolerated and provides promising early signals of therapeutic activity with an Objective Response Rate (ORR) of 72.7% (8/11) and a Disease Control Rate (DCR) of 90.9% (10/11). Nine patients had a PD-L1 Tumour Proportion Score (TPS) of <50% and this group reported an encouraging ORR of 66.7% and DCR of 88.9%. Patients with a PD-L1 of <50% represent approximately two-thirds of the 1L NSCLC patient population and are less responsive to anti-PD-1 therapy compared to patients with a PD-L1 TPS of ≥50%.

Additional data from INSIGHT-003 is expected to be presented throughout calendar year 2023. For more information on the study, please see the poster titled ‘Feasibility of eftilagimod alpha (soluble LAG-3 protein) combined with standard-of-care-therapy in advanced non-small-cell lung cancer (NSCLC). Initial results from INSIGHT 003’ in the Posters & Publications section of Immutep’s website.

About INSIGHT-003

INSIGHT-003 is an investigator-initiated study conducted by the Institute of Clinical Cancer Research IKF at Krankenhaus Nordwest in Frankfurt. It is being run as the third arm (Stratum C) of the ongoing Phase I INSIGHT trial with Prof. Dr. Salah-Eddin Al-Batran as lead investigator. The study is evaluating a triple combination therapy in front line non-small cell lung cancer patients consisting of efti administered subcutaneously in conjunction with an existing approved standard-of-care combination of anti-PD-1 therapy (pembrolizumab) and chemotherapy (carboplatin and pemetrexed) delivered intravenously. The trial will assess the safety, tolerability, and initial efficacy of the combination.