On February 6, 2023 LIDDS AB (publ) ("LIDDS"or the "Company") reported the preliminary outcome of the righs issue with preferential rights for the shareholders (the "Rights Issue"), which subscription period ended today (Press release, Lidds, FEB 6, 2023, View Source [SID1234626890]). The subscription breakdown shows that 24,967,268 shares, corresponding to 35.0 MSEK or approximately 71.9 percent of the Rights Issue, were subscribed for with or without the exercise of subscription rights. The Rights Issue was secured to approximately 95.7 percent through issue gurantees and the Company will therefore obtain approximately 46.5 MSEK before issue costs.

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"I would like to thank all existing shareholders who have participated in the rights issue for your continued support and extend a warm welcome to new shareholders. The rights issue provides a significant reinforcement to the Company’s continued development of Nanodotax and Nanoimod and enables intensified work with the out-licensing of the Phase III project Liproca Depot", says Anders Månsson, CEO of LIDDS.

The subscription period in the Rights Issue ended today the 6 February 2023 and a preliminary breakdown shows that 24,967,268 shares, corresponding to 35.0 MSEK or approximately 71.9 percent of the Rights issue, were subscribed for with or without the exercise of subscription rights. No investors who have issued guarantees will preliminary be allocated any shares. The Rights Issue was secured to approximately 95.7 percent through issue guarantees and the Company will therefore obtain approximately 46.5 MSEK before issue costs.

The final outcome of the Rights Issue is expected to be announced on Wednesday 8 February 2023. Allocation of shares that were subscribed for without the exercise of subscription rights will be done according to the principles described in the prospectus that was prepared in connection with the Rights Issue and was published on 17 January 2023. Those who will be allocated shares without the support of subscription rights will be notified after the allocation meeting held by the Board of Directors on 8 February 2023 through contract note. Nominee shareholders will receive notification of allotment in accordance with the respective nominee’s routines. Allocated shares should be paid according to the instructions on the contract note.

Advisors
Erik Penser Bank AB is financial advisor to LIDDS in connection with the share issue and Setterwalls Advokatbyrå AB is legal advisor.

On February 6, 2023 Atreca, Inc. (Atreca) (NASDAQ: BCEL), a clinical-stage biotechnology company focused on developing novel therapeutics generated through a unique discovery platform based on interrogation of the active human immune response, and Xencor, Inc. (NASDAQ: XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies and cytokines for the treatment of cancer and autoimmune diseases, reported that, as part of their existing strategic collaboration, they have mutually selected the first program combining an Atreca-discovered antibody with Xencor’s XmAb bispecific Fc domain and a cytotoxic T-cell binding domain (CD3) (Press release, Xencor, FEB 6, 2023, View Source [SID1234626889]).

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Under the terms of their 2020 collaboration, Atreca generates novel, tumor-binding antibodies from the immune responses of cancer patients and identifies the antibodies’ targets. Xencor then engineers Atreca’s antibodies into T-cell engaging bispecific antibodies that bind to and activate the CD3 co-receptor on T cells, and characterizes these novel XmAb bispecific antibodies to identify candidates for further development. The program announced today is the first of up to two joint programs that can be mutually selected for further development and commercialization, with each partner sharing 50% of costs and profits. Atreca will lead clinical development, regulatory and commercialization activities for this program, and the second potential joint program would be advanced by Xencor. In addition, the agreement allows for each partner to pursue up to two programs arising out of the collaboration independently.

The joint program announced today is based on APN-346958, an Atreca-discovered antibody. APN-346958 targets a novel RNA-binding protein and is tumor-reactive in at least 50% of samples for six tumor types evaluated, including: colorectal, thyroid, head and neck, urothelial, melanoma and brain cancer. In preclinical studies, the XmAb bispecific antibodies engineered against APN-346958’s target have demonstrated potent anti-tumor activity. Atreca and Xencor expect to name a candidate from the program later this year, and Atreca targets an investigational new drug (IND) submission by early 2025.

"The advancement of this program into joint development is a key milestone in our collaboration with Xencor," said Stephen Gould, Ph.D., Chief Scientific Officer of Atreca. "We continue to believe that our respective approaches have the potential to be highly complementary, given the abundance of novel antibody-target pairs generated by Atreca’s discovery platform and the plug-and-play nature of Xencor’s XmAb bispecific antibody platform. We are excited to continue working with Xencor to advance this program and generate additional programs combining Atreca antibodies and Xencor CD3 bispecific engineering."

"We are using our modular protein engineering platforms to create a new generation of XmAb bispecific antibodies that can act directly and selectively against solid tumors with cytotoxic T cell engagement," said John Desjarlais, Ph.D., Senior Vice President and Chief Scientific Officer at Xencor. "Today’s announcement speaks to the productivity of our ongoing collaboration with Atreca, and we look forward to evaluating additional molecules engineered with antibodies presented by Atreca’s unique and differentiated discovery platform."

On February 6, 2023 Vincerx Pharma, Inc. (Nasdaq: VINC), a biopharmaceutical company aspiring to address the unmet medical needs of patients with cancer through paradigm-shifting therapeutics, reported that Vincerx’s management team will present the company’s corporate overview and participate in one-on-one investor meetings at the SVB Securities Global Biopharma Conference, to be held virtually from February 14-16, 2023 (Press release, Vincerx Pharma, FEB 6, 2023, View Source [SID1234626888]).

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SVB Securities Global Biopharma Conference Presentation Details
Date: Thursday, February 16, 2023
Time: 1:40 p.m. ET
Webcast: View Source

An archived webcast will be accessible in the Investors section of the Company’s website for approximately 90 days following the event.

On February 6, 2023 Isoray, Inc. (NYSE AMERICAN: ISR), a medical technology company and innovator in seed brachytherapy, reported the successful completion of the merger with privately-held Viewpoint Molecular Targeting, Inc (Press release, Viewpoint Molecular Targeting, FEB 6, 2023, https://viewpointmt.com/isoray-completes-merger-with-viewpoint-molecular-targeting-to-advance-new-treatment-paradigm-in-targeted-precision-oncology-medicine/ [SID1234626887]). The combined companies’ focus will be the advancement of cancer treatments using radiation, radiopharmaceuticals, and imaging technologies so that precision, targeted medical doses are delivered directly to cancer patient tumor sites. Viewpoint Molecular Targeting CEO Thijs Spoor has been named Chief Executive Officer and outgoing Isoray CEO Lori Woods assumed the role of Chairperson of the Board of Directors of the combined companies. The closing of the all-stock transaction became effective on February 3, 2023.

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Outgoing Isoray CEO Lori Woods said, "This merger represents an important milestone for Isoray. The merger with Viewpoint Molecular Targeting demonstrates our commitment to build on our shared belief of treating cancers from the inside out while providing personalized targeted treatment options for cancer patients. We look forward to delivering a path forward that speaks to the continued growth of the combined companies benefitting patients and the doctors who treat them, while increasing stockholder value."

Incoming Isoray CEO Thijs Spoor commented, "The merger of Isoray and Viewpoint represents a powerful combination of two complementary businesses in the field of radiopharmaceuticals. The mission of the combined company is to further develop the role of Cesium-131 for the treatment of a variety of cancers while we expand on our exciting and novel pipeline of proprietary targeting peptides to diagnose tumors in order to deliver powerful Targeted Alpha Therapies (TAT’s). The use of alpha-particle radiation with proprietary targeted delivery agents has the potential to transform the treatment paradigm of patients suffering from early stage cancers."

About the Merger
At the closing of the merger, each issued and outstanding share of common stock of Viewpoint was converted into 3.1642 shares of Isoray common stock for a total of 136,545,075 shares, or approximately 49%, of the 278,657,841 shares of outstanding common stock of Isoray. Other than cash paid in lieu of fractional shares which amounted to $14.80, there was no cash consideration paid in connection with the merger.

Concurrent with the closing of the merger, the size of Isoray’s Board of Directors was increased to five members comprised of Lori Woods (Chairperson), Thijs Spoor, Dr. Frank Morich, Robert Williamson, and Michael McCormick.

On February 6, 2023 Veracyte, Inc. (Nasdaq: VCYT) reported that it will release financial results for the fourth quarter and full-year 2022 after the close of market on Wednesday, February 22, 2023 (Press release, Veracyte, FEB 6, 2023, View Source [SID1234626886]). Company management will host a conference call and webcast to discuss financial results and provide a general business update at 4:30 p.m. Eastern Time on the same day.

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The conference call will be webcast live from the company’s website and will be available via the following link: View Source A webcast replay will be available following the conclusion of the live broadcast and will be accessible on the company’s website at View Source

The conference call dial-ins can be accessed by registering at: https://register.vevent.com/register/BIbe54a1af06be4083968e88a7edfb6679