Aravive Announces $10.0 Million Investment by Eshelman Ventures, LLC and Appointment of Dr. Eshelman as Executive Chairman of the Aravive Board of Directors

On January 3, 2021 Aravive, Inc. (Nasdaq: ARAV), a late clinical-stage oncology company developing targeted therapeutics to treat metastatic disease reported that the company’s Chairman, Fred Eshelman, Pharm.D., through Eshelman Ventures, LLC, agreed to purchase a pre-funded warrant to purchase 4,545,455 shares of the company’s common stock at a price of $2.20 per share, which was the consolidated closing bid price of the company’s common stock on The Nasdaq Global Select Market on December 31, 2021 (Press release, Aravive, JAN 3, 2022, View Source [SID1234597963]). The investment strengthens the company’s balance sheet by approximately $10.0 million, enhancing the company’s financial flexibility and liquidity ahead of multiple anticipated clinical milestones throughout 2022 for each of the company’s clinical programs. The investment is expected to close on January 5, 2022.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

"I am encouraged by the company’s progress in 2021 to advance our lead product candidate," stated Dr. Eshelman, Chairman of Aravive, Inc. "Through this investment I am affirming my commitment to the future of Aravive and eagerly look forward to the continued rapid progress of developing batiraxcept as a novel therapeutic option for patients with metastatic disease."

As of December 31, 2021, Dr. Eshelman was the beneficial owner of approximately 3,806,098 shares of the company’s common stock, or approximately 18.2% of the total outstanding shares of the company. Although Dr. Eshelman’s investment in the company is not conditioned on shareholder approval, the Nasdaq Stock Market where the company’s shares are listed requires the company to seek shareholder approval to allow the exercise of the pre-funded warrant if such exercise would result in Dr. Eshelman beneficially owning in excess of 20% of the voting power of the company’s common stock.

Pursuant to the terms of the investment agreement executed among the company, Dr. Eshelman, and Eshelman Ventures, LLC and consistent with the terms of past investments by Eshelman Ventures, LLC, the company is required to register the resale of the shares of common stock issuable upon exercise of the pre-funded warrant.

Additionally, Dr. Eshelman was appointed the Executive Chairman of Aravive having served as the Non-Executive Chairman of the board since April 2020. In his new role as Executive Chairman, Dr. Eshelman will continue to work with Chief Executive Officer, Gail Mcintyre, Ph.D., and senior management of the Company, to help shape and execute the Company’s strategy and direction, as well as other key business initiatives, subject in all cases to the direction of the Board of Directors.

"Dr. Eshelman and I have worked closely together for over 20 years and in various companies to bring a number of products to market," stated Gail McIntyre, Ph.D., DABT, Chief Executive Officer of Aravive. "I am looking forward to working closely with Dr. Eshelman to hopefully bring batiraxcept to market."

Exact Sciences to participate in J.P. Morgan Healthcare Conference

On January 3, 2021 Exact Sciences Corp. (NASDAQ: EXAS) reported that company management will participate in the following virtual conference and invited investors to participate by webcast (Press release, Exact Sciences, JAN 3, 2022, View Source [SID1234597962]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

J.P. Morgan Healthcare Conference
Presentation followed by Q&A on Wednesday, January 12, 2022 at 5:15 p.m. ET
The webcast can be accessed in the investor relations section of Exact Sciences’ website at www.exactsciences.com.

Neurocrine Biosciences to Present at the 40th Annual J.P. Morgan Healthcare Conference

On January 3, 2022 Neurocrine Biosciences, Inc. (Nasdaq: NBIX) reported that it will present at the virtual 40th Annual J.P. Morgan Healthcare Conference at 11:15 a.m. Eastern Time on Monday Jan. 10, 2022 (Press release, Neurocrine Biosciences, JAN 3, 2022, View Source [SID1234597961]). Kevin Gorman, Chief Executive Officer, will present at the conference .

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The live presentation will be webcast and may be accessed on the Company’s website under Investors at www.neurocrine.com. A replay of the presentation will be available on the website approximately one hour after the conclusion of the events and will be archived for approximately one month.

Onxeo appoints Julien Miara as new interim CEO

On January 3, 2022 Onxeo S.A. (Euronext Growth Paris: ALONX, First North Copenhagen: ONXEO), ("Onxeo" or "the Company"), a clinical-stage biotechnology company specializing in the development of innovative drugs targeting tumor DNA Damage response (DDR), reported the appointment of Julien Miara as interim Chief Executive Officer, effective January 3rd, 2022, following approval from the Board of Directors (Press release, Onxeo, JAN 3, 2022, View Source [SID1234597960]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

Julien Miara is a Principal at Invus SAS, the independent adviser to Invus Public Equities, L.P. He is also member of the Board of Directors of Onxeo. He has more than 10 years of experience in Finance and biotechnology. Julien Miara will work closely with Dr. Shefali Agarwal, Chairwoman of the Board of Directors who has extensive experience in drug development, to ensure that the company is progressing according to the strategic plan laid out by the Board of Directors and prepare for a successful transition to the next CEO.

The company’s Board of Directors is actively working on recruiting Onxeo’s next CEO who will focus on bringing expeditiously AsiDNA to the patients to respond to their high unmet medical need, develop the rich pre-clinical pipeline such as OX401 and provide Onxeo with international visibility.

Dr. Agarwal said: "I look forward to working with the high performing team under the supervision of Julien Miara, in the next phase of research and development for AsiDNA. I believe that Onxeo’s scientific vision and approach will drive the continued success of the company, as we work together to deliver promising new options for patients"

MaaT Pharma to Present at H.C. Wainwright BioConnect 2022 Virtual Conference

On January 3, 2022 MaaT Pharma (EURONEXT: MAAT – the "Company"), a French clinical-stage biotech and a pioneer in the development of microbiome-based ecosystem therapies dedicated to improving survival outcomes for patients with cancer, reported that its CEO and co-founder, Hervé Affagard will present the company at the upcoming H.C. Wainwright Bioconnect Virtual Conference held January 10-13, 2022 (Press release, MaaT Pharma, JAN 3, 2022, View Source [SID1234597959]).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

                  Schedule Your 30 min Free Demo!

The presentation will be available on-demand through the H.C. Wainwright conference portal, starting at 7 am EST/1:00 pm CET on Monday, January 10, 2022.

A replay of the presentation will also be made accessible in the investors’ section of the company’s website at www.maatpharma.com from Friday, January 14, 2022 and for 90 days after the event.