On September 26, 2022 Galera Therapeutics, Inc. (Nasdaq: GRTX), a clinical-stage biopharmaceutical company focused on developing and commercializing a pipeline of novel, proprietary therapeutics that have the potential to transform radiotherapy in cancer, reported that tumor outcomes data from its Phase 3 ROMAN trial of avasopasem for severe oral mucositis (SOM) and final data from its Phase 2 AESOP trial of avasopasem for chemoradiotherapy-induced esophagitis will be highlighted in two presentations at the upcoming 2022 American Society for Radiation Oncology (ASTRO) Annual Meeting, taking place October 23-26, 2022 in San Antonio, Texas (Press release, Galera Therapeutics, SEP 26, 2022, View Source [SID1234621420]). Additionally, poster presentations will highlight the Phase 2 EUSOM trial of avasopasem for SOM in Europe and the ongoing GRECO-1 trial of rucosopasem for non-small cell lung cancer.
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Presentation Details
Title: Tumor Outcomes for ROMAN: Phase 3 Trial of Avasopasem Manganese (GC4419) for Severe Oral
Mucositis (SOM) in Patients Receiving Chemoradiotherapy (CRT) for Locally Advanced Head and Neck Cancer (LAHNC)
Abstract Number: 280
Presenter: Carryn M. Anderson, M.D., University of Iowa Hospitals & Clinics
Session Title: H&N 3 – Toxicity Mitigation and HPV-Unrelated Head and Neck Cancer – Life Beyond De-Intensification
Session Date and Time: Wednesday, October 26, 2022 | 12:40 p.m. CDT
Session Location: Henry B. Gonzalez Convention Center, Room 214
Title: AESOP: Phase 2 Open-Label Trial of Avasopasem Manganese (GC4419) for Reduction of Esophagitis in Patients Receiving Chemoradiotherapy for Nonmetastatic Lung Cancer
Abstract Number: 1124
Presenter: Bryan G. Allen, M.D., Ph.D., University of Iowa Hospitals & Clinics
Session Title: Lung 3 – Optimizing Radiation Dose, Volume, and Concomitant Systemic Agents
Session Date and Time: Wednesday, October 26, 2022 | 10:50 a.m. CDT
Session Location: Henry B. Gonzalez Convention Center, Room 303
Poster Q&A Details
Title: GRECO-1: Phase 1/2 Study of Stereotactic Body Radiation Therapy (SBRT) with or without Rucosopasem (GC4711) for Early Stage, Peripheral or Centrally Located Non-Small Cell Lung Cancer (NSCLC)
Abstract Number: 2841
Presenter: Puneeth Iyengar, M.D., Ph.D., UT Southwestern Medical Center
Session Title: Poster Q&A 01 – Lung Cancer and DEIH
Session Date and Time: Sunday, October 23, 2022 | 4:45 p.m. CDT
Session Location: Henry B. Gonzalez Convention Center, Exhibit Hall 1
Title: EUSOM: Phase 2 Trial of Avasopasem Manganese (GC4419) for Oral Mucositis in Patients Receiving Chemoradiotherapy for Locally Advanced, Nonmetastatic Head and Neck Cancer
Abstract Number: 2687
Presenter: Jordi Giralt, M.D., Ph.D., Vall d’Hebron University Hospital
Session Title: Poster Q&A 09 – Head & Neck Cancer and Health Services Research
Session Date and Time: Wednesday, October 26, 2022 | 10:30 a.m. CDT
Session Location: Henry B. Gonzalez Convention Center, Exhibit Hall 1
The titles of the abstracts are currently available in the ASTRO digital program, with the full abstracts available on Friday, October 21, 2022, at 5 p.m. CDT.