On September 8, 2022 Kazia Therapeutics Limited (NASDAQ: KZIA; ASX: KZA), an oncology-focused drug development company, reported that final data from its phase II study of paxalisib in patients with newly diagnosed glioblastoma will be the subject of an oral presentation at the upcoming annual congress of the European Society for Medical Oncology (ESMO) (Free ESMO Whitepaper), which will be held in person from 9-13 September 2022 in Paris, France (Press release, Kazia Therapeutics, SEP 8, 2022, View Source [SID1234619299]).

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The oral presentation will summarise key findings of the completed phase II study of paxalisib in glioblastoma, which was previously the subject of a poster presentation at the American Society for Clinical Oncology (ASCO) (Free ASCO Whitepaper) Annual Meeting in Chicago, IL, in June 2022. The presentation will provide additional detail on pharmacokinetics and pharmacodynamics. The presentation will be delivered by Professor John de Groot, Division Chief of Neuro-Oncology at the University of California, San Francisco, one of the principal investigators on the study.

On September 8, 2022 EXUMA Biotech, Corp., a clinical-stage biotechnology company discovering and developing cell and gene immunotherapies for solid and hematological tumors, reported that its Chief Business Officer and Head of Finance, Dr. Gregory Wade, will provide a corporate presentation at 11:25 AM ET on Wednesday, September 14, 2022, as part of the annual Baird Global Healthcare Conference in New York (Press release, EXUMA Biotechnology, SEP 8, 2022, View Source [SID1234619298]). Dr. Wade will be available for one-on-one investor meetings during the conference. Please contact your Baird representative to schedule a meeting with Greg.

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On September 8, 2022 Entrepreneurial Accelerator Program (EAP) portfolio company Oleolive, Inc. reported that it has been awarded a Small Business Technology Transfer (STTR) Phase 1 $400,000 research grant from the National Cancer Institute for "Chemosensitization of Glioblastoma by Propentofylline (Press release, Oleolive, SEP 8, 2022, View Source [SID1234619296])." Drs. Nhan Tran and Joseph Loftus, investigators at Mayo Clinic and experts in Glioblastoma Multiforme (GBM), collaborated with Oleolive on the proposal.

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Propentofylline (PPF) was originally tested in multiple clinical trials for Alzheimer’s disease but, although shown to be safe and effective, was not brought to the commercial market. PPF is considered a repurposed drug, defined as a drug developed for one indication and repositioned to treat another, in this case GBM. Repurposed drugs require less money and time for development and overall costs much less compared to research and development of new drugs.

GBM is a brain cancer with no effective therapeutics that claims the lives of over 15,000 Americans each year. GBM has poor clinical outcomes due to therapy-resistant tumor cells leading to recurrence; therefore, therapeutic strategies that enhance tumor cell chemosensitivity are essential for improved patient outcomes. This project will evaluate if PPF increases sensitization of GBM tumor cells to chemotherapy. This research could lead to a therapeutic strategy to extend survival for GBM patients beyond the current average of 1.25 years.

On September 8, 2022 The MedTech company NeoDynamics reported that received approval for its innovative pulse biopsy system NeoNavia from the US Food and Drug Administration, FDA (Press release, NeoDynamics, SEP 8, 2022, View Source [SID1234619295]).

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The US breast biopsy market is estimated to reach $830 million by 2025.

"The FDA approval for NeoNavia is a major milestone for NeoDynamics and a stamp of quality for both the product and NeoDynamics as a whole," said Anna Eriksrud, CEO of NeoDynamics. "The US represents the potentially largest market for the product, where we now also can build on the experience gained with the system in Europe. Preparation for the launch is ongoing and we expect to begin introducing the system to clinicians and potential partners within the next few months."

NeoDynamics intends to work with US clinics to further document the product in clinical practice to support its marketing and sales strategy. A similar strategy is successfully being executed on in Europe, demonstrating the benefits of the product while forging relationships with important clinics to facilitate a broad acceptance and uptake of the system.

NeoNavia is an innovative biopsy system that uses a patented pulse technology for controlled and accurate needle insertion, which is based on research at Karolinska Institutet. NeoDynamics’ goal is for the pulse technology to become the new standard for ultrasound-guided breast biopsies. The product has CE approval in Europe, where it is in clinical use.

On September 8, 2022 Myeloid Therapeutics, Inc. ("Myeloid"), a clinical stage mRNA-immunotherapy company harnessing the power of myeloid and innate biology to engineer novel therapies that elicit a broad immune response for cancer and autoimmune diseases, reported that the Company will participate in the following investor conferences (Press release, Myeloid Therapeutics, SEP 8, 2022, View Source [SID1234619294]):

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Morgan Stanley 20th Annual Global Healthcare Conference, September 12-14th, 2022, in NY
Jefferies Cell & Genetic Medicine Summit, September 29-30th, 2022, in NY