F. Hoffmann-La Roche Announces Half Year Results 2022

On July 21, 2022 F. Hoffmann-La Roche Ltd. (hereafter "Roche") [Head Office: Basel, Switzerland. CEO: Severin Schwan] reported its half year results 2022 (January 1 – June 30, 2022) (Press release, Chugai, JUL 21, 2022, View Source [SID1234616834]).

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Roche owns 59.89% of Chugai’s outstanding shares (61.14% of voting rights) as of the end of June 2022.

Its investor update and presentation materials can be found on its website (View Source).
Chugai’s performance for the period of January 1 to June 30, 2022 is included in the announced Roche Group’s results.

Cerus Corporation to Release Second Quarter 2022 Financial Results on August 4, 2022

On July 21, 2022 Cerus Corporation (Nasdaq: CERS) reported that its second quarter 2022 financial results will be released on Thursday, August 4, 2022, after the close of the stock market (Press release, Cerus, JUL 21, 2022, View Source [SID1234616833]). The Company will host a conference call and webcast at 4:30 P.M. ET that afternoon, during which management will discuss the Company’s financial results and provide a general business overview and outlook.

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To listen to the live webcast and view the presentation slides, please visit the Investor Relations page of the Cerus website at View Source Participants may register for the call here. While not required, interested participants are encouraged to join 10 minutes prior to the start of the event.

A replay will be available on Cerus’ website and will be available approximately three hours after the call through August 18, 2022.

Arbutus to Report Second Quarter 2022 Financial Results and Provide Corporate Update

On July 21, 2022 Arbutus Biopharma Corporation (Nasdaq: ABUS), a clinical-stage biopharmaceutical company leveraging its extensive virology expertise to develop novel therapeutics that target specific viral diseases, reported that it has scheduled its second quarter 2022 financial results and corporate update for Thursday, August 4, 2022 (Press release, Arbutus Biopharma, JUL 21, 2022, View Source [SID1234616832]). The schedule for the press release and conference call/webcast are as follows:

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•Q2/2022 Press Release: Thursday, August 4, 2022 at 7:30 a.m. ET
•Q2/2022 Conference Call/Webcast: Thursday, August 4, 2022 at 8:45 a.m. ET
•Domestic Dial-In Number: (800) 715-9871
•International Dial-In Number: (646) 307-1963
•Conference ID Number: 5109143
A live webcast of the conference call can be accessed through the Investors section of Arbutus’ website at www.arbutusbio.com.

An archived webcast will be available on the Arbutus website after the event. Alternatively, you may access a replay of the conference call by calling (800) 770-2030 or (609) 800-9909, and reference conference ID: 5109143.

High-Yield GMP-Compliant Primary Cell Bank Established for Miltuximab®

On July 21, 2022 GlyTherix reported the successful completion of its high-yield GMP-grade stable cell line development program for its proprietary antibody Miltuximab in partnership with international biologics manufacturer GenScript ProBio (New Jersey, USA) (Press release, Glytherix, JUL 21, 2022, View Source [SID1234616831]).

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Establishing a stable, high-yield cell line suitable for commercial production of clinical-grade monoclonal antibody is a critical milestone for the Company. The Chinese Hamster Ovary (CHO) cell clones selected for Miltuximab cell banking have reached titres of above 8g/L. Work is now continuing on the process development program for scale-up of Miltuximab manufacturing at 100L-bioreactor scale for the Company’s upcoming Australian Phase I trial.

Miltuximab will be used in a Phase Ib trial as an antibody theranostic. Antibody labelled with 89-Zirconium will be used as an imaging agent to select patients showing tumor targeting. This will be followed by patients being offered Miltuximab labelled with 177-Lutetium as a therapeutic dose.

To find out more about GlyTherix’s technology and clinical program, visit www.glytherix.com

GlyTherix is seeking investors who would like to participate in the company’s Series A funding round.

This project received grant funding from the Australian Government.

[Ad hoc announcement pursuant to Art. 53 LR] Roche: Change in the Board of Directors and Corporate Executive Committee in Spring 2023

On July 21, 2022 Roche (SIX: RO, ROG; OTCQX: RHHBY) reported that Christoph Franz has decided not to seek re-election to the Board of Directors at the AGM in March 2023 (Press release, Hoffmann-La Roche, JUL 21, 2022, View Source [SID1234616829]). The Board of Directors intends to propose Severin Schwan as new Chairman at the AGM and has appointed Thomas Schinecker as new Roche CEO effective 15 March 2023.

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Christoph Franz was elected to the Roche Board of Directors in 2011 and has served as its Chairman since 2014: "After serving twelve years on the Board of Directors, nine of which as Chairman, I have decided not to seek re-election to the Board next year. We have achieved many important milestones and with the conclusion of Roche’s 125th anniversary, it is now the right time for a change in leadership. I am proud of the significant contributions Roche has made in fighting the pandemic during the last two and a half years. I am also pleased that we could secure long term stability in our shareholder structure with the repurchase of Roche shares from Novartis. With the strong pipelines of innovative products in both our Pharma and Diagnostic businesses, we are set for continued growth in the future."

The Roche Board of Directors will propose Severin Schwan as new Chairman at the AGM on 14 March 2023. Severin Schwan has been a member of the Corporate Executive Committee since 2006 and has served as CEO of the company since 2008. He has been a member of the Roche Board of Directors since 2013. Severin Schwan: "I have very much appreciated the close and trusting collaboration with Christoph and would like to thank him. I am honoured to stand for the position of Chairman of the Roche Board of Directors and will continue to dedicate all my efforts to the future of this company."

André Hoffmann, Vice-Chairman of the Board of Directors and representative of the Oeri and Hoffmann shareholder group with pooled voting rights: "Thanks to Christoph’s long term strategic vision, he has steered our company confidently and successfully through challenging times. Roche’s continued success is in no small part due to his personal contributions. I would like to thank him sincerely, also in the name of our families. As in the past, we are able to secure the succession to the Chairman and CEO roles with excellent leaders from within Roche. This is a great quality of our company."

Effective 15 March 2023, the Board of Directors has appointed Thomas Schinecker, currently CEO of the Diagnostics Division, as CEO of Roche succeeding Severin Schwan. Thomas Schinecker holds a PhD in Molecular Biology and has been working for Roche in different leadership positions since 2003. He became CEO of the Diagnostics Division and a member of the Corporate Executive Committee in August 2019.

Severin Schwan: "I am very pleased that the Board has appointed Thomas as the new Roche CEO. He is a highly qualified successor who has been working for Roche in leadership positions around the globe for twenty years. Thomas successfully set up our Diagnostics Division for the future. Under his leadership our Diagnostics organisation also made considerable contributions in fighting the COVID-19 pandemic."

Thomas Schinecker: "I am deeply honoured by the Board’s decision and the trust placed in me. I am delighted to carry on working closely with Roche colleagues and the Corporate Executive Committee. Like we’ve done for the last 125 years, I am excited about the future innovations we will bring to patients around the globe."