On January 8, 2021 Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) reported its fourth quarter earnings conference call will be webcast on Friday, February 5, 2021 at 8:30 a.m. ET (Press release, Zimmer Holdings, JAN 8, 2021, View Source [SID1234573727]). A news release detailing the quarterly results will be made available that day at 6:30 a.m. ET.

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The live audio webcast can be accessed via Zimmer Biomet’s Investor Relations website at https://investor.zimmerbiomet.com. It will be archived for replay following the conference call.

Individuals in the U.S. and Canada who wish to dial into the conference call may do so by dialing (888) 312-9837 and entering conference ID 7278985. For a complete listing of international toll-free and local numbers, please visit https://investor.zimmerbiomet.com. A digital recording will be available after the completion of the conference call, from February 5, 2021 to April 6, 2021. To access the recording, U.S. callers should dial (888) 203-1112 and international callers should dial +1 (719) 457-0820, and enter the Access Code ID 7278985.

On January 8, 2021 CASI Pharmaceuticals, Inc. (Nasdaq: CASI), a U.S. biopharmaceutical company focused on developing and commercializing innovative therapeutics and pharmaceutical products, reported that Dr. Wei-Wu He, Chairman and Chief Executive Officer of CASI Pharmaceuticals, will be presenting at the H.C.Wainwright Bioconnect Conference. Details for the virtual conferences are as follows (Press release, CASI Pharmaceuticals, JAN 8, 2021, https://www.prnewswire.com/news-releases/casi-pharmaceuticals-inc-to-present-at-hc-wainwright-bioconnect-conference-301203238.html [SID1234573726]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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H.C.Wainwright Bioconnect Conference
Date: Monday, January 11th
Time: 6:00 AM (ET)

Webcast or external link of the company presentations will be available under "Events & Presentations" in the "Investors Relations" section of CASI’s website. Archived replays will be available for approximately 90 days following the event.

On January 8, 2021 Frontier Medicines, Corp., a precision medicine company drugging challenging protein targets to develop breakthrough medicines that change the course of human diseases, reported that Chris Varma, Ph.D., Frontier’s co-founder, chairman, and CEO, will present a webcasted company overview at the 39th Annual J.P. Morgan Healthcare Conference on Wednesday, January 13, 2021 at 2:35 p.m. ET (Press release, Frontier Medicines, JAN 8, 2021, View Source [SID1234573725]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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A live audio webcast of the presentation will be available for access in the News & Media section of Frontier’s website at View Source An archived replay will be accessible for 30 days following the event.

On January 8, 2021 Denovo Biopharma LLC, a pioneer in applying precision medicine to development of innovative therapies, reported dosing of the first patient in its biomarker guided Phase 3 clinical study evaluating the DB102 (enzastaurin) in combination with temozolomide and radiation as first line therapy to treat newly-diagnosed glioblastoma multiforme (GBM) (Press release, Denovo Biopharma, JAN 8, 2021, View Source [SID1234573724]). This randomized, double-blind, placebo-controlled global study is to enroll more than 300 patients and the primary outcome measure is overall survival in patients with Denovo Genomic Marker 1 (DGM1). This GBM study has received Phase 3 permission from regulatory agencies from US, Canada, and China, and also gained FDA’s Fast Track designation last year.

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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"This GBM study is the second global Phase 3 trial of DB102 for patients with cancer following our first global Phase 3 trial of DB102 for patients with diffuse large B-cell lymphoma (DLBCL). In both trials, we use DGM1 to identify the patients who will receive the most benefits from DB102 therapy in combination regimens," said Zane Yang, M.D., Denovo’s Chief Medical Officer. "GBM remains to be one of the deadliest cancers and the first line drug treatment still relies on temozolomide as the backbone — many promising anticancer drugs, including anti-PD-1 drugs, have failed to improve upon temozolomide’s efficacy. I am hopeful that our innovative approach can bring new hope to patients with this difficult-to-treat condition that continues to have a significant unmet need."

For more information on the DB102 ENGAGE clinical study, visit View Source

About DB102
DB102 (enzastaurin) is an orally available investigational first-in-class small molecule, serine/threonine kinase inhibitor of the PKC beta, PI3K, and AKT pathways that has been studied in more than 3,000 patients across a range of solid and hematological tumor types. DB102 was originally developed by Eli Lilly and for which Denovo has acquired worldwide rights. DB102 received Orphan Drug Designation in DLBCL and glioblastoma multiforme (GBM) from the FDA and EMA and Fast Track Designation from the FDA.

About Glioblastoma
Glioblastoma Multiforme (GBM) is the most common type of adult primary malignant brain cancer, with 18,000 newly-diagnosed patients in the US and 13,000 deaths annually. Standard treatment for patients with newly diagnosed GBM can include surgery followed by radiation and chemotherapy, but treatment options are limited. The five-year survival rate of patients with GBM is less than five percent.

On January 8, 2021 Strata Oncology, Inc., a precision oncology company advancing molecular indications for cancer therapies, reported that Dan Rhodes, Ph.D., co-founder and Chief Executive Officer of Strata Oncology will present at the upcoming virtual J.P. Morgan 39th Annual Healthcare Conference on January 13, 2021, at 8:05 a.m. Eastern Time (Press release, Strata Oncology, JAN 8, 2021, View Source [SID1234573723]).

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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