Distributors Announce Proposed Opioid Settlement Will Proceed to Next Phase

On September 4, 2021 AmerisourceBergen (NYSE: ABC), Cardinal Health (NYSE: CAH) and McKesson (NYSE: MCK) reported that, under the previously announced proposed settlement agreement and process designed to resolve the opioid claims of state and local governmental entities, they have determined that enough states have agreed to settle to proceed to the next phase (Press release, Cardinal Health, SEP 4, 2021, View Source [SID1234591442]). Under the proposed settlement agreement and process, all U.S. States, territories, and Washington DC were given 30 days to join the settlement, except West Virginia which settled previously with the companies. As of August 21, 2021, 42 out of 49 states, all 5 territories and Washington DC had affirmatively signed on to the agreement.

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This next phase is notice to the subdivisions, and the subdivision sign-on period. During this phase, each participating state will offer its political subdivisions, including those that have not sued, the opportunity to participate in the settlement for an additional 120-day period, which ends January 2, 2022. After the conclusion of the political subdivision sign-on period, each company will independently determine whether a sufficient number of political subdivisions have joined for the settlement to proceed to implementation.

If the conditions are satisfied, the settlement would become effective 60 days after the distributors determine that there is sufficient participation to proceed. During this 60-day period, the participating states and the distributors would cooperate to obtain consent judgments in each participating state embodying the terms of the settlement. The companies will make their first annual settlement payment into escrow on or before September 30, 2021, and the payment will be disbursed following the effective date or returned to distributors if the settlement does not become effective. The final payment amount will depend on several factors, including the final participation rate of states and political subdivisions.

The companies believe that this settlement framework will allow them to focus their attention and resources on the safe and secure delivery of medications and therapies while expediting the delivery of meaningful relief to affected communities.

Dr. Reddy’s Laboratories enters into definitive agreement with Citius Pharmaceuticals, Inc. to sell its rights to anti-cancer agent E7777 (denileukin diftitox)

On September 4, 2021 Dr. Reddy’s Laboratories Ltd. (BSE: 500124, NSE: DRREDDY, NYSE: RDY, NSEIFSC: DRREDDY, along with its subsidiaries together referred to as "Dr. Reddy’s"), reported that it has entered into a definitive agreement with Citius Pharmaceuticals, Inc. ("Citius") pursuant to which it sold all of its rights to E7777 (an engineered IL-2-diphtheria toxin fusion protein) and certain related assets (Press release, Dr Reddy’s, SEP 4, 2021, View Source [SID1234587243]).

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Under the terms of agreement, Dr. Reddy’s will receive $40 million upfront upon the closing of the transaction, followed by approval milestone payment of up to $40 million related to the CTCL (cutaneous T-cell lymphoma) indication approval and up to $70 million for additional indication approvals. Further, Dr. Reddy’s will receive certain sales-based milestones and tiered earn-out payments.

In March 2016, Dr. Reddy’s had acquired the exclusive global rights (excluding Japan and Asia) to the investigational anti-cancer agent E7777 from Eisai Co. Ltd.

Erez Israeli, Chief Executive Officer, Dr. Reddy’s, said: "Addressing unmet patient needs in oncology remains a prime focus area for us. E7777 has significant potential as an important component of systemic therapy for CTCL and other cancers. Post acquiring from Eisai, significant progress was made on the CTCL development front. We are confident of Citius’ ability to realize the full potential of E7777 in the treatment of CTCL as well as in their ability to develop this promising drug for additional oncology and immuno-oncology indications."

G1 Therapeutics to Participate in Two Upcoming September Conferences

On September 3, 2021 G1 Therapeutics, Inc. (Nasdaq: GTHX), a commercial-stage oncology company, reported that the Company will participate in two upcoming virtual investor conferences in September (Press release, G1 Therapeutics, SEP 3, 2021, View Source [SID1234587578]).

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On September 10, 2021, G1 will participate in the Citi 16th Annual BioPharma Virtual Conference. There is no webcast associated with this conference.

On September 13, 2021, G1’s Chief Executive Officer Jack Bailey will present at the H.C. Wainwright 23rd Annual Global Investment Conference. This will be available on demand beginning the morning of September 13, 2021. The webcast will be accessible on the Events & Presentations page of View Source

Molecular Partners to Present at Upcoming Healthcare Investor Conferences

On September 3, 2021 Molecular Partners AG (SIX: MOLN, NASDAQ: MOLN), a clinical-stage biotech company developing a new class of custom-built protein drugs known as DARPin therapeutics, reported that its Chief Executive Officer, Patrick Amstutz, Ph.D., will present at two upcoming virtual healthcare investor events in September 2021 (Press release, Molecular Partners, SEP 3, 2021, View Source [SID1234587260]).

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Conference Presentation Details:

Event: Morgan Stanley 19th Annual Global Healthcare Conference
Date/Time: Friday, September 10, 11:00 AM – 11:45 AM ET (5:00 PM – 5:45 PM CET)
Event: H.C. Wainwright 23rd Annual Global Investment Conference
Date/Time: September 13-15, 2021; Presentation available on demand from Sept. 13, 7:00 AM ET (1:00 PM CET)
All webcasted presentations will be made available on the Molecular Partners website.

QIAGEN to enter the DAX – Germany’s leading stock market index

On September 3, 2021 QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) reported it has been chosen to be included in the DAX (Deutscher Aktienindex), the leading German stock market index in Germany (Press release, Qiagen, SEP 3, 2021, View Source;Germanys-Leading-Stock-Market-Index/default.aspx [SID1234587258]).

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"Joining the ranks of Germany’s top publicly listed companies is a great milestone and achievement for QIAGEN," said Thierry Bernard, Chief Executive Officer of QIAGEN N.V. "The relevance of molecular testing to fight disease, develop medicines and conquer scientific frontiers has never been stronger. Our employees are the reason for this achievement and have never been more committed to achieving our vision at QIAGEN of making improvements in life possible."

Roland Sackers, Chief Financial Officer of QIAGEN added: "Our inclusion in the DAX 40 is a recognition of the progress QIAGEN has made to deliver long-term profitable growth and create value for shareholders and other stakeholders. Even more important has been the contribution of QIAGEN’s solutions to increasing our knowledge about the biology of life and improving outcomes for patients. This goes to the heart of what our employees do every day and making a significant impact on daily life around the world."

QIAGEN was built on a revolutionary way to extract DNA – composed of the building blocks of life – from a wide range of biological samples. As a spinout of the University of Duesseldorf, QIAGEN has become a global company on track to achieve more than $2 billion in sales in 2021. With about 6,000 employees worldwide, QIAGEN’s corporate headquarter is in Venlo, the Netherlands, while the operational headquarters site is in Hilden, Germany.

QIAGEN is implementing a successful growth strategy that aims to create significant value for its stakeholders, including shareholders. The company’s portfolio of Sample to Insight portfolio address the growing molecular testing needs of customers across the continuum from research and pharmaceutical R&D in the life sciences to clinical molecular diagnostics.

The changes in the DAX, which is being expanded to include the 40 largest companies based on market capitalization, is set to take place on Monday, September 20, 2021. This is also the date when QIAGEN will no longer be included in Germany’s MDAX, which will now be the index for the next 50 companies based on market capitalization after the DAX.

QIAGEN also continues as a member of Germany’s TecDAX, which is comprised of the 30 largest German companies from the technology sector. Additionally, QIAGEN’s Global Shares are listed on the New York Stock Exchange (NYSE), making it one of only a few companies listed on exchanges in both countries.