On July 19, 2021 Scandion Oncology A/S reported that invites investors, analysts, and media to a virtual Capital Markets Day on September 8, 2021 (Press release, Scandion Oncology, JUL 19, 2021, View Source;2021,c3386979 [SID1234584932]).

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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During the day, Scandion Oncology’s executive management will provide a corporate strategy update, a deep dive into the clinical strategy and the business opportunities to pursue our goal of becoming The Cancer Drug Resistance Company.

Specific details will be provided in August, but please save the date or register now at View Source

On July 16, 2021 VERAXA Biotech GmbH (former Velabs Therapeutics GmbH), a leading company in innovative ADC engineering and functional antibody screening, reported that it has entered into a partnership agreement with Quadira Biosciences AG, Zug, Switzerland, to jointly develop a suite of novel ADCs for the treatment of oncological conditions (Press release, Veraxa Biotech, JUL 16, 2021, View Source [SID1234586668]). The collaboration will leverage both the advantages of VERAXA’s advanced and proprietary position-true click-chemistry-based drug conjugation technology in combination with Quadira’s superior 3D cellular assay and assessment systems. The agreement provides that VERAXA will be entitled to upfront payments and royalties from the worldwide sale of products resulting from the collaboration. Further details of the agreement were not disclosed.

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Quadira Biosciences AG is a Joint Venture between abc biopply AG, a Swiss biotech company specializing in the standardization of biological components and complex 3D cell culture systems and Xlife Sciences AG, a Swiss based biotech company. Quadira will, under the partnership, have exclusive access to abc biopply’s proprietary 3D CoSeedis technology platform, a new standard in the industrial application of 3D cell culture systems for preclinical drug validation.

VERAXA Biotech is a leading pioneer of microfluidic technology for the ultra-fast screening of functional antibodies. The company has developed superior microfluidic hardware and processes to screen for modulatory mAbs on complex target proteins such as GPCRs. In contrast to all other technologies available, VERAXA combines binding and functional assessment in 1 single step and unravels precious therapeutic hits out of entire immune repertoires that consists of millions of B cells in less than 48 hours. Just recently, VERAXA acquired Araxa Biosciences GmbH, a biotech company with innovative and proprietary protein engineering and click-chemistry based drug coupling technologies to expand its preclinical antibody capacities from early screening to later stage antibody engineering and to sharpen its profile in personalized medicine and precision oncology. With the novel ADC technology, VERAXA can perform precise site-specific antibody labeling with almost any drug at any position and highest reproducibility. The company has several ADC in production and testing with superior cytotox profiles as compared to benchmark molecules.

"This partnership with Quadira is an ideal and fully complementary constellation adding significant value to our top ADC candidate suite by in depths assessment through Quadira’s unmet gold standard 3D assay platform," said Christoph Antz, CEO of VERAXA. "The combination of VERAXA’s first class novel ADC candidates with POC assessment data from our 3D cell culture systems will strongly speed up the whole ADC drug development process. We will generate a suite of best-in-class ADC drug candidates with a significantly de-risked development trajectory and high preclinical maturity," adds Arne Faiss, CEO of both abc biopply and Quadira.

On July 16, 2021 IntegraGen (FR0010908723 – ALINT – Eligible PEA PME), a company specializing in decoding the human genome which performs interpretable genomic analyzes for academic and private laboratories, reported its unaudited turnover for the first half of 2021 (Press release, Integragen, JUL 16, 2021, View Source [SID1234585219]).

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Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The unaudited first half turnover amounted to 4,816 k€, up 2% compared to the first half of 2020 (4,706 k€). This growth was achieved despite the sharp slowdown in general economic activity during the first half of 2021 compared with H1 2020, whose first quarter was less affected by the pandemic. This sustained growth demonstrates the robustness of IntegraGen’s business model.

R&D sequencing activities continued to progress at a moderate pace, driven by whole genome sequencing projects performed for the European customers. While sequencing activities associated with the external platforms operated by IntegraGen benefited from the demand of sequencing projects linked to the pandemic, oncology-related clinical research activities, in particular the sales of interpretation software, slowed significantly for the same reason.

The company’s cash position at the end of June 2021 was 4,272 k€, a decrease of nearly 850 k€ compared to the cash position as of December 31, 2020. This variation was due to change in working capital requirements and investments, particularly in the company’s quality systems to obtain several certifications which will lead to increase revenues generated from customers in regulated industries.

Finally, the orders booked as of June 30, 2021 were significantly higher compared to the same period of 2020, setting the stage for a sustained growth in activities during the second half of 2021. The integration of IntegraGen into the OncoDNA Group, which acquired a majority of the company’s shares in 2020 through a friendly takeover bid, also enhances the prospects for IntegraGen’s additional sales growth as a result of the ability to leverage the Group’s subsidiaries and distributors.

Bernard Courtieu, CEO of IntegraGen, said: "The business we generated during the first half of 2021 confirms that despite the ongoing pandemic that continues to disrupt our activities, the trajectory of our revenue growth is sustainable, albeit at a lower level, with prospects for a significant recovery. The acquisition of a majority of the company’s shares by the Belgian company OncoDNA results in commercial and operational synergies which will enable IntegraGen to continue its development and growth as a vital part of the OncoDNA Group."

The financial results for the first half of 2021 will be published on October 8, 2021.

On July 16, 2021 Jiangsu Hailai Xinchuang Medical Technology reported that it closed a $77 million Series C funding to advance its Tumor Treating Fields (TTF) electrical pulse technology for cancer (Press release, Jiangsu Hailai Xinchuang Medical Technology, JUL 16, 2021, View Source [SID1234584924]). TTF is designed to interfere with cancer cell division. Hailai has started a multi-center China clinical trial of EFE-G100 in glioblastoma patients, with positive initial results. The company will report an interim analysis from the data in 2022. The latest funding was led by YF Capital, with participation from Temasek, Lilly Asia Ventures, 3H Health Investment, CITIC and Qiming.

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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On July 16, 2021 Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) reported that it will report its second-quarter 2021 financial results on Thursday, July 29, 2021 after the financial markets close. The company will host a conference call and webcast at 5:30 p.m. ET (Press release, Vertex Pharmaceuticals, JUL 16, 2021, View Source [SID1234584921]). To access the call, please dial (866) 501-1537 (U.S.) or +1 (720) 545-0001 (International).

Schedule your 30 min Free 1stOncology Demo!
Discover why more than 1,500 members use 1stOncology™ to excel in:

Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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The conference call will be webcast live and a link to the webcast can be accessed through Vertex’s website at www.vrtx.com in the "Investors" section. To ensure a timely connection, it is recommended that participants register at least 15 minutes prior to the scheduled webcast. An archived webcast will be available on the company’s website.