On May 27, 2021 "In China, the biopharma industry has been entering a period of incredibly rapid development," says Dr. PC Zhu, Founder and CEO of ATLATL, the leading Innovation Center in Shanghai (Press release, Mabwell Biotech, MAY 27, 2021, View Source [SID1234580715]). "Scores of companies with rich pipelines and robust capabilities have listed or filed listing applications in the past few years, and the portfolio companies at our campus have raised tremendous funds, just like my previous incubator in Boston." Mabwell, a typical case of such a start-up company, reported that has raised $279 million (RMB ¥1.97 billion) from a series of investors, ranking in the Top 5 Venture Raises of 2020, and is currently preparing for listing on SSE STAR market.

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Mabwell is representative of the success of Chinese biopharma start-ups, ranking 5th on the list of the Top 10 money raisers of 2020 around the world, as ranked by Fiercebiotech (released in Mar. 2021) and 2nd in the list of the Top 20 Venture Raises of 2020 in ex-US regions, as listed in LavoieHealthScience (released in Oct. 2020). Founded in 2017, Mabwell focuses on the discovery, development, manufacture, and commercialization of innovative biologics and has set-up 9 subsidiaries to accelerate the industrialization process. Currently, Mabwell has a pipeline of 15 biologics in the areas of immunology, oncology, metabolic diseases, ophthalmology, and infectious diseases, and 8 products in the clinical stage are expected to be commercialized by 2023-2026. The first product, Adalimumab biosimilar, is expected to be marketed in 2021. Earlier this year, Mabwell obtained the IND acceptance for an anti-ST2 monoclonal antibody, making it the first Chinese company to apply this target IND submission and receive acceptance.

For venture capital, pipeline and capability may be the most immediate concerns. A high value pipeline means a promising future and generous returns. In addition, a company with comprehensive capabilities guarantees smooth sailing in every process, especially clinical development, which is significant in the fierce, competitive field of drug development. With expansion of the local market and investment, and growing support from the Chinese government, an increasing number of biopharma start-ups in China are expected to raise more money to strengthen pipelines and improve capabilities. With this trend, it is easily foreseeable that Chinese biopharma companies will be even more competitive in the global market in the next decade.

On May 27, 2021 Scholar Rock (NASDAQ: SRRK), a clinical-stage biopharmaceutical company focused on the treatment of serious diseases in which protein growth factors play a fundamental role, reported that management will participate in the following upcoming investor conferences (Press release, Scholar Rock, MAY 27, 2021, View Source [SID1234580714]):

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Jefferies Virtual Healthcare Conference on Wednesday, June 2nd, 2021 at 11:00 a.m. ET.
Goldman Sachs Annual Global Healthcare Conference on Wednesday, June 9th, 2021 at 2:10 p.m. ET.
BMO Biopharma Day: Rare Disease Panel, Central Nervous System on Tuesday, June 22nd, 2021 at 10:30 a.m. ET.
A live webcast of presentations at the Jefferies and Goldman Sachs conferences may be accessed by visiting the Investors & Media section of the Scholar Rock website at View Source An archived replay of the webcast will be available on the Company’s website for approximately 90 days following the presentation.

On May 27, 2021 Sesen Bio (Nasdaq: SESN), a late-stage clinical company developing targeted fusion protein therapeutics for the treatment of patients with cancer, reported that Sesen Bio President and CEO Dr. Thomas Cannell will participate in a fireside chat at the Jefferies Virtual Healthcare Conference on June 4, 2021 (Press release, Sesen Bio, MAY 27, 2021, View Source [SID1234580713]).

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Event: Jefferies Virtual Healthcare Conference
Date: June 4, 2021
Time: 8:30 – 8:55 AM ET

A live webcast of the Company’s presentation will be accessible from the Investors & Media section of Sesen Bio’s website, www.sesenbio.com. An archived replay of the webcast will be available on the Company’s website for 60 days after the conference.

On May 27, 2021 As interest and demand for more accurate prostate cancer imaging grows, and with the approval of the first Ga-68 PSMA based prostate imaging agent late last year1, Cardinal Health Nuclear & Precision Health Solutions (Cardinal Health) and Telix Pharmaceuticals (US) Inc. (Telix) reported that they have developed an in-depth white-paper, entitled: "Moving beyond the Myth: Meeting the growing demand for Ga-68 radiopharmaceuticals (Press release, Cardinal Health, MAY 27, 2021, View Source [SID1234580712])." The paper shines a light on the pathways for radio-isotope production, distribution and clinical application, as well as highlighting the extensive systems already in place to help ensure potential demand for Ga-68 imaging products is met.

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Despite major disruption caused by COVID-19, 2020 saw two new drug applications (NDA) and an approval by the U.S. Food and Drug Administration (FDA) for the first 68Ga- PSMA-11 product for prostate cancer imaging albeit restricted to use in two academic institutions1. Since then, interest has been building in anticipation of other gallium-based imaging options currently under review by the FDA.

"A key to satisfying the demand for this isotope lies in having a robust network of radiopharmacies like Cardinal Health," said Dr. Christian Behrenbruch, Chief Executive Officer of Telix Pharmaceuticals Limited. "There is a perception in the industry that supply chain issues may limit the availability of gallium-based radiopharmaceuticals. Whilst this may have been true historically, this is no longer the case. The strength and power of gallium lies in its flexibility, with production by either cyclotron or generator. This offers greater flexibility and opportunity for scale than other purely cyclotron-based isotopes. Subject to regulator approval, we look forward to offering state-of-the-art diagnostic imaging to U.S. men living with prostate cancer, and Cardinal Health’s radiopharmacy network and infrastructure will be vital in facilitating nationwide access."

Cardinal Health Nuclear & Precision Health Solutions offers an extensive network of over 130 pharmacies, of which more than 110 are licensed to process 68Ga. Besides distribution efficiencies, Cardinal Health’s Accutrac system tracks doses during transit from the pharmacy to the site of care, enabling a greater than 99% on-time delivery record to help ensure doses are delivered where they are needed, when they are needed. "Patient and physician satisfaction is our top priority," says Tiffany Olson, President of the Cardinal Health Nuclear & Precision Health Solutions business. "Telix Pharmaceuticals is developing gallium-based innovations to advance prostate cancer imaging, and Cardinal Health is ready to help meet that demand."

On May 27, 2021 ADC Therapeutics SA (NYSE: ADCT), a commercial-stage biotechnology company leading the development of novel antibody drug conjugates (ADCs) to treat hematological malignancies and solid tumors, reported that Chris Martin, Chief Executive Officer, will present at the Jefferies Virtual Healthcare Conference on Thursday, June 3, 2021, at 8:30 a.m. ET (Press release, ADC Therapeutics, MAY 27, 2021, View Source [SID1234580711]).

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A live webcast of the presentation will be available via the Events & Presentations page in the Investors section of ADC Therapeutics’ website, ir.adctherapeutics.com. A replay of the webcast will be available for approximately 30 days.