On April 29, 2021 ERYTECH Pharma (Nasdaq & Euronext: ERYP) (the "Company"), a clinical-stage biopharmaceutical company developing innovative therapies by encapsulating therapeutic drug substances inside red blood cells, reported that it has entered into definitive agreements with several health-care focused institutional and accredited investors for the purchase and sale of 1,034,483 units ("Units"), each Unit consisting of four ordinary shares in the form of American Depositary Shares (each an "ADS") and three warrants, each to purchase one ordinary share (each a "Warrant"), in a registered direct offering to specified categories of investors, described below (Press release, ERYtech Pharma, APR 29, 2021, View Source [SID1234578753]). The subscription price for one Unit is $29.00 (€24.03), corresponding to $7.25 (€6.01) per ADS and associated 0.75 warrant. Each ADS represents the right to receive one ordinary share, €0.10 nominal value, of the Company. The Warrants have an exercise price of €7.50 ($9.05) per share, will be immediately exercisable upon issuance and will expire two years from the issuance date. The closing of the offering is expected to occur on or about May 4, 2021, subject to satisfaction of customary closing conditions.

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On April 26, 2021 Cannabics Pharmaceuticals Inc. (OTCQB: CNBX), a global leader in the development of cancer related cannabinoid-based medicine, reported the launching of a new research program for the development of a Melanoma antitumor targeting medicine (Press release, Cannabics Pharmaceuticals, APR 29, 2021, View Source [SID1234578752]). The announcement comes amidst the recent completion of a series of preclinical experiments within the company’s in-house research facilities demonstrating promising antitumor results on Melanoma cell lines.

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The launching of the new research program for the development of Melanoma treatment follows a previous development by the company of Cannabics RCC-33, a proprietary formula for the treatment of Colorectal Cancer, who demonstrated a 33% reduction in tumor volume and a 35% increase in survival rate in recent in-vivo experiments in mice.

CNBX launches new research for Melanoma Drug Candidate

Gabriel Yariv, Cannabics Pharmaceuticals President & COO said: "The company has unique expertise and experience allowing it to develop new antitumor formulas from our built-to-spec in-house drug discovery platform. Accordingly, following our decision to develop an additional antitumor drug candidate to target Melanoma, we were able to produce high quality preclinical data, as well as identify several promising findings that we now plan to further investigate. This method of evaluation organically points towards the path of developing a new drug candidate for the treatment of Melanoma."

Eyal Barad Cannabics Pharmaceuticals’ Co-founder and CEO commented: "The company plans to use this new data to initiate in-vivo animal model studies to be included in a future product package that we intend to submit to the US Food and Drug Administration along with a Pre-IND Meeting request."

Melanoma is the most serious type of skin cancer, particularly given its characteristic of spreading deeper into the skin and into other organs. According to the Skin Cancer Foundation the estimated five-year survival rate for U.S. patients whose melanoma is detected early is about 99%, and it is estimated that some 200,000 new cases of Melanoma will be diagnosed in the US in 2021 alone.

On April 29, 2021 Oasmia Pharmaceutical AB, an innovation-focused specialty pharmaceutical company, reported that the Annual Report for the shortened financial year of May to December 2020 has been published (Press release, Oasmia, APR 29, 2021, View Source [SID1234578751]). The Annual Report is attached as a PDF and is available on the company’s website, View Source

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For More Information:
Francois Martelet, Chief Executive Officer
Phone: +46 18-50 54 40
E-mail: [email protected]

On April 29, 2021 The Offeror, Sanofi (Euronext: SAN and NYSE: SNY) and Kiadis (Euronext Amsterdam and Brussels: KDS) reported that during the Post-Closing Acceptance Period, which expired at 17:40 (CET) today, 1,436,922 Shares were tendered under the Offer, representing approximately 2.35% of the aggregate issued and outstanding ordinary share capital of Kiadis on a Fully Diluted basis (Press release, Sanofi, APR 29, 2021, View Source [SID1234578749]). Including the 58,051,156 Shares already held by Sanofi following Settlement, this is a total of 59,488,078 Shares, representing approximately 97.39% of the aggregate issued and ordinary outstanding share capital of Kiadis on a Fully Diluted basis.

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Settlement

Shareholders who accepted the Offer shall receive the Offer Price for each Tendered Share tendered during the Post-Closing Acceptance Period and transferred (geleverd) to the Offeror for acceptance pursuant to the Offer, under the terms and conditions set out in the Offer Memorandum. Reference is made to Section 5.12 (Post-Closing Acceptance Period) of the Offer Memorandum.

Settlement of the Shares and payment of the Offer Price will take place on 3 May 2021. Following settlement of the Shares tendered during the Post-Closing Acceptance Period, the Offeror will (directly or indirectly) hold 59,488,078 Shares, representing approximately 97.39% of the aggregate issued and outstanding ordinary share capital of Kiadis on a Fully Diluted basis.

ING Bank N.V. has been acting as settlement and exchange agent in connection with the Offer.

Buy-Out

Since the Offeror owns more than 95% of the Shares, the Offeror will initiate the statutory Buy-Out in an expeditious manner in order to obtain 100% of the Shares. Reference is made to section 6.11(c) (Buy-Out) of the Offer Memorandum.

Delisting

As a result of the acquisition of more than 95% of the Shares by the Offeror, the listing and trading of the Shares on Euronext will be terminated.
In consultation with Euronext, it has been decided that the last day of trading of the Shares will be on 24 May 2021. This means that the termination of the listing of the Shares shall be effective as of 25 May 2021. Reference is made to Sections 6.11(a) (Intentions following the Offer being declared unconditional) and Section 6.11(b) (Liquidity and delisting) of the Offer Memorandum.

Announcements

Any announcement contemplated by the Offer Memorandum will be issued by press release. Any press release issued by the Offeror will be made available on the website of the Offeror (www.sanofi.com). Any press release issued by Kiadis will be made available on the website (www.kiadis.com).

Subject to any applicable requirements of the applicable rules and without limiting the manner in which the Offeror may choose to make any public announcement, the Offeror will have no obligation to communicate any public announcement other than as described above.

Offer Memorandum, Position Statement and further information
This announcement contains selected, condensed information regarding the Offer and does not replace the Offer Memorandum and/or the Position Statement. The information in this announcement is not complete and additional information is contained in the Offer Memorandum and the Position Statement.
Digital copies of the Offer Memorandum are available on the website of the Offeror (www.sanofi.com) and digital copies of the Position Statement are available on the website of Kiadis (www.kiadis.com). Such websites do not constitute part of, and are not incorporated by reference into, the Offer Memorandum. Copies of the Offer Memorandum and the Position Statement are on request also available free of charge at the offices of Kiadis and the Settlement Agent at the addresses below:

Kiadis
Kiadis Pharma N.V.
Paasheuvelweg 25A
1105 BP Amsterdam
The Netherlands

Settlement Agent
ING Bank N.V.
Bijlmerdreef 106
1102 CT Amsterdam
The Netherlands

On April 29, 2021 Vedanta Biosciences, a leading clinical-stage microbiome company developing a new category of oral therapies using rationally defined bacterial consortia manufactured from clonal cell banks, reported that members of its management team will participate in the SVB Leerink Biopharma Private Company Connect Event being held virtually Thursday, May 6 – Friday, May 7, 2021 (Press release, Vedanta Biosciences, APR 29, 2021, View Source [SID1234578747]).

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Event: SVB Leerink Biopharma Private Company Connect Event
Date: Thursday, May 6 – Friday, May 7, 2021