Propanc Biopharma Receives Investment from Institutional Investor

On July 28, 2020 Propanc Biopharma, Inc. (OTC: PPCB) ("Propanc" or the "Company"), a biopharmaceutical company developing new cancer treatments for patients suffering from recurring and metastatic cancer, reported that the company received an additional investment tranche from a lead institutional investor to support company operations and working capital needs (Press release, Propanc, JUL 28, 2020, View Source [SID1234562437]). To date, a, total of $550,000 has been funded by the institutional investor of a $3,000,000 financing agreement, as the company prepares its lead product candidate, PRP, for a Phase IB, First-In-Human study, in advanced cancer patients suffering from solid tumors.

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"We are pleased to receive ongoing financial support from our lead institutional investor as we transition PRP into the clinic," said Carlo Campiciano, Propanc’s Chief Financial Officer, "The investment will be utilized to support our operations, as well as preparing for undertaking R&D activities, including validation of a pharmacokinetics method and a quality assurance review, as we advance towards the finished product manufacture of PRP for our upcoming clinical study, which we hope to commence early 2021."

"We recognize and appreciate the support of our shareholders, as we undertake an important transformation to a clinical stage biopharma company," said James Nathanielsz, Propanc’s Chief Executive Officer. "With our attractive R&D tax incentive benefit for local and approved overseas activities from the Australian Government, we have an opportunity to recoup a portion of our development expenses upon the achievement of near-term development milestones for PRP," said James Nathanielsz.

Curis to Release Second Quarter 2020 Financial Results and Hold Conference Call on August 4, 2020

On July 28, 2020 Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer, reported that the Company will release its second quarter 2020 financial results on Tuesday, August 4, 2020, after the close of US markets (Press release, Curis, JUL 28, 2020, View Source [SID1234562435]). Management will host a conference call on the same day at 4:30 p.m. ET.

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To access the live conference call, please dial (888) 346-6389 from the United States or (412) 317-5252 from other locations, shortly before 4:30 p.m. ET. The conference call can also be accessed on the Curis website at www.curis.com in the ‘Investors’ section. A replay of the financial results conference call will be available on the Curis website shortly after completion of the call.

CytomX Therapeutics to Announce Second Quarter 2020 Financial Results

On July 28, 2020 CytomX Therapeutics, Inc. (Nasdaq: CTMX), a clinical-stage oncology-focused biopharmaceutical company pioneering a novel class of investigational antibody therapeutics based on its Probody therapeutic technology platform, reported second quarter 2020 financial results on Thursday, August 6, 2020, after the close of U.S. markets. Following the announcement, the company will host a conference call beginning at 5:30 p.m. ET to discuss the results.

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Participants may access the live audio webcast of the teleconference from the "Investors & News" section of CytomX’s website at View Source Please access the website 15 minutes prior to the start of the call to download and install any necessary audio software.

Audio Conference Call:

U.S. Dial-in Number: (877) 809-6037

International Dial-in Number: (615) 247-0221

Conference ID: 5399347
An archived webcast replay will be available on the Company’s website from August 6, 2020, until August 13, 2020.

Synlogic Announces Second Quarter 2020 Conference Call & Webcast

On July 28, 2020 Synlogic, Inc. (Nasdaq: SYBX), a clinical stage company bringing the transformative potential of synthetic biology to medicine, reported the Company will release its second quarter 2020 financial results before the market opens on Thursday, August 6, 2020 (Press release, Synlogic, JUL 28, 2020, View Source [SID1234562433]). The press release will be followed by a conference call at 8:00 am ET, which will be open to the public via telephone and webcast. During the conference call, the Company will review its financial results and provide a corporate update.

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The conference call dial-in numbers are (844) 815-2882 for domestic callers and (213) 660-0926 for international callers. The conference ID number for the call is 5673797. Participants may access the live webcast via a link on the Synlogic website in the Events Calendar of the Investors and Media section. For those unable to participate in the conference call or webcast, a replay will be available for 30 days on the Company’s website.

Anixa Biosciences Breast Cancer Vaccine Technology Nearing FDA Submission

On July 28, 2020 Anixa Biosciences, Inc. (NASDAQ: ANIX), a biotechnology company focused on the treatment and prevention of cancer and infectious diseases, reported that its prophylactic breast cancer vaccine is making progress towards clinical trials (Press release, Anixa Biosciences, JUL 28, 2020, View Source [SID1234562432]).

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Anixa and Cleveland Clinic intend to file the Investigational New Drug (IND) Application with the US Food and Drug Administration by the end of the current quarter. Despite government-mandated laboratory closures, disruptions and constraints due to the coronavirus pandemic, there has not been a significant delay in this vaccine’s development timeline.

This vaccine technology was invented by a research team from Cleveland Clinic, led by Dr. Vincent Tuohy, the Mort and Iris November Distinguished Chair in Innovative Breast Cancer Research in the Department of Inflammation and Immunity at Cleveland Clinic’s Lerner Research Institute.

The underlying technology takes advantage of self-proteins that have a function at certain times in life, but then become "retired" and disappear from the body. One such protein, alpha-lactalbumin, is expressed only in the mammary glands during lactation and then disappears once lactation ceases. Dr. Tuohy discovered that this protein is abnormally expressed again when a woman contracts breast cancer, especially Triple Negative Breast Cancer (TNBC), the most deadly form of this disease. Dr. Tuohy postulated that if women could be immunized against this protein, after the age of childbirth, the immune system could be trained to destroy the cancer cells as they arise, thus making it difficult for the cancer to gain critical mass. Early studies to test this theory demonstrated highly significant prevention of breast cancer in animal models.

"We are extremely excited to move forward with this technology. At the current time, the bulk of the IND application is completed. The main portion that remains to be finished is the CMC section (Chemistry, Manufacture and Control)," stated Dr. Amit Kumar, President and CEO of Anixa Biosciences. "After completion of the IND, it will be reviewed by our regulatory experts and committees and then filed with the FDA. We have already had two pre-IND meetings with the FDA as this is a novel vaccine technology."