Tyme Technologies to Present at BIO Digital from June 8-12, 2020

On May 27, 2020 Tyme Technologies, Inc. (NASDAQ: TYME), an emerging biotechnology company developing cancer metabolism-based therapies (CMBTs), reported that management will present a corporate overview for 2020 at BIO Digital from June 8-12. For 2020, the BIO International Convention has transitioned to a new, virtual event format (Press release, TYME, MAY 27, 2020, View Source [SID1234558572]). The Company will present its corporate overview for 2020 with a special focus on multiple growth opportunities driven by advances in the science of cancer metabolism, pivotal trial in pancreatic cancer, clinical trial in ultra-rare metastatic sarcoma and expanding clinical plans for its lead candidate SM-88 (racemetyrosine) in pancreatic, prostate, breast and/or hematological cancers.

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Event: BIO Digital
Place: View Source
Presentation Date: June 8-12, 2020

The presentation will be accessible on the events page under the Investor Relations section of Tyme Technologies’ website at www.tymeinc.com. There is no webcast for this event.

Moderna to Present at Upcoming Investor Conferences

On May 27, 2020 Moderna, Inc., (Nasdaq: MRNA) a clinical stage biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients, reported its participation in the following upcoming virtual investor conferences (Press release, Moderna Therapeutics, MAY 27, 2020, View Source [SID1234558571]):

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Jefferies Global Healthcare Conference on Wednesday, June 3, 2020 at 10:30 a.m. ET.
Goldman Sachs 41st Annual Global Healthcare Conference on Thursday, June 11, 2020 at 2:10 p.m. ET.
A live webcast of each presentation will be available under "Events and Presentations" in the Investors section of the Moderna website at investors.modernatx.com. A replay of each webcast will be archived on Moderna’s website for 30 days following the presentation.

Bicycle Therapeutics to Present at Upcoming Investor Conferences

On May 27, 2020 Bicycle Therapeutics plc (NASDAQ: BCYC), a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle) technology, reported that management will participate in fireside chats at the following virtual investor conferences in June (Press release, Bicycle Therapeutics, MAY 27, 2020, View Source [SID1234558570]):

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Early/Late Stage Pipeline Development - Target Scouting - Clinical Biomarkers - Indication Selection & Expansion - BD&L Contacts - Conference Reports - Combinatorial Drug Settings - Companion Diagnostics - Drug Repositioning - First-in-class Analysis - Competitive Analysis - Deals & Licensing

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Jefferies Global Healthcare Conference on Wednesday, June 3, 2020 at 3:00 p.m. ET
Goldman Sachs 41st Annual Global Healthcare Conference on Thursday, June 11, 2020 at 1:20 p.m. ET
A live webcast of each presentation will be accessible in the Investors & Media section of Bicycle’s website at www.bicycletherapeutics.com. Archived replays of the webcasts will be available for 90 days following the presentation dates.

EdiGene and Immunochina Announce Research and Development Collaboration to Develop Allogeneic CAR-T Therapy for Cancer

On May 27, 2020 EdiGene, Inc., which develops genome editing technologies to accelerate drug discovery and develop novel therapeutics for a broad range of diseases, and Immunochina,a company dedicated to innovative gene and cellular technology,reported that they have formed a research and development collaboration to develop allogeneic CAR-T therapy for cancer (Press release, EdiGene, MAY 27, 2020, View Source [SID1234558569]).

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Under this partnership, both companies will combine EdiGene’s expertise in genome editing and allogeneic T-cell process with Immunochina’s expertise in innovative CAR-T technology to develop potentially best-in-class allogeneic CAR-T therapeutics. Terms are not disclosed.

"EdiGene is a leading gene-editing company with cutting edge technology platform. It is our great pleasure to work with this team," said Ting He, Ph.D.,founder and CEO of Immunochina, "Make the Incurable Curable, which is Immunochina’s vision. We have accumulated considerable experience in late-stage hematological malignancies, with two IND approvals. Although a number of break throughs have been made by autologous T cells lately, allogeneic T cells could also play an important role in the future. The cooperation is a big step for both teams, and I believe we will make exciting discoveries together."

"We are excited to collaborate with Immunochina, one of the leading clinical-stage CAR-T companies," said Dong Wei, Ph.D.,CEO of EdiGene, "We believe that allogeneic T-cell therapeutics has tremendous potential, by offering innovative T-cell therapies ‘off the shelf’ with more effective quality control and lower cost. By combining the expertise of EdiGene and Immunochina, we will be well positioned to develop such therapeutics and advance to clinics, one step closer to help the cancer patients in need."

AbCellera Closes $105 Million Series B Financing to Further Advance World-Leading Antibody Drug Discovery Platform

On May 27, 2020 AbCellera reported that it has closed a US$105 million Series B financing (Press release, AbCellera, MAY 27, 2020, View Source [SID1234558568]). The financing was led by OrbiMed and current investor DCVC Bio, with an investor syndicate that includes Viking Global Investors, Peter Thiel, Founders Fund, Eli Lilly and Company, University of Minnesota, and Presight Capital . With the proceeds of the financing, AbCellera will expand its capacity and invest in technologies that complement and extend its proprietary antibody discovery engine.

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"Drug development takes too long, fails too often, and costs too much. With the backing of visionary investors, we will double-down on our strategy of making long-term investments in technology and teams that are needed to put drug development on the fast track," said Carl Hansen, Ph.D., CEO of AbCellera. "We’re building a modern operating system for drug developers to ensure the best science is translated quickly into new therapies for patients."

AbCellera screens, selects, and analyzes millions of naturally produced antibodies to find next-generation drug candidates. By accelerating the arduous and unpredictable process of antibody drug discovery with rigorous machine learning and data science, AbCellera enhances the entire biologics ecosystem, from small biotechs to global pharmaceutical companies.

"AbCellera has embarked on a long-term project to make it possible to solve biological challenges with the speed and urgency that they all too obviously require," said Peter Thiel, entrepreneur and investor.

"AbCellera is at the intersection of biology, technology, and AI, allowing it to make new antibody drug discovery advancements, which we previously couldn’t dream of, possible," said John Hamer, Managing Partner, DCVC Bio. "From developing therapeutics for neurological diseases to COVID-19 and everything in-between, AbCellera is transforming the antibody discovery process, delivering more possibilities in less time and with less expense. We continue to be enthusiastic supporters of its progress."

AbCellera will use the funds to deepen its technology stack, creating and aggregating novel tools to propel the development of new biological modalities, from monoclonal, multi-specific, and single-domain antibodies, to bioconjugates, gene-encoded biologics, and cell therapies.

The funds will also support the growth of AbCellera’s facilities and teams, including:

Expanding its workforce;
Opening a new 48,000-square-foot R&D facility in 2021; and
Building a GMP manufacturing facility for production of biologics for clinical testing.
AbCellera has successfully completed more than 55 programs, delivering high-quality antibody drug candidates for a wide variety of drug targets, including historically challenging multi-pass membrane protein targets, such as GPCRs and ion channels. The company has generated lead therapeutic antibody candidates for unmet needs in various disease areas including cancer, immuno-oncology, neurodegeneration, pain, fibrosis, and metabolic disorders