Kezar Life Sciences Strengthens Executive Team with the Appointment of Noreen R. Henig, MD as Chief Medical Officer

On May 4, 2020 Kezar Life Sciences, Inc. (Nasdaq: KZR), a clinical-stage biotechnology company discovering and developing novel small molecule therapeutics to treat unmet needs in autoimmunity and cancer, reported the appointment of Noreen R. Henig, MD as its Chief Medical Officer (Press release, Kezar Life Sciences, MAY 4, 2020, View Source [SID1234557124]). As an integral member of the Company’s Executive Leadership team, Dr. Henig will oversee all aspects of the Company’s clinical development, regulatory and medical affairs.

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"Noreen brings with her a depth and breadth of expertise in clinical practice, translational science, clinical development, and medical affairs, and we are thrilled to welcome her to the Kezar team," said John Fowler, Kezar’s Chief Executive Officer. "Her proven leadership skills, deep understanding of immunology and rare diseases, and profound appreciation of the patient voice will make a significant impact, and I look forward to working in partnership with her as we continue to advance our novel therapies for a wide range of autoimmune diseases and cancers."

Noreen Roth Henig, M.D. is a seasoned leader whose career spans clinical practice, academic medicine, translational science, clinical development, medical and regulatory affairs. She currently serves on the Board of Avidity Biosciences and most recently served as Chief Medical Officer of Breath Therapeutics, which was acquired by Zambon SpA in 2019. As CMO, Dr. Henig built and led the clinical team and was responsible for all development activities including clinical and non-clinical science, clinical operations, regulatory, project management, and medical affairs. Prior to joining Breath, Dr. Henig was Chief Medical Officer at ProQR Therapeutics where she brought two unique RNA oligonucleotides through early clinical trials in rare diseases. Before ProQR, Dr. Henig spent 2008 through 2014 at Gilead Sciences where she held roles with increasing responsibility, including building and leading a global medical affairs organization, strategic development of clinical trials Phase 2-4, regulatory strategy, corporate development, leadership of key alliances and commercial strategy. Prior to joining industry, Dr. Henig spent nearly 10 years in leadership roles within academic medicine at Stanford University and California Pacific Medical Center. She is a board-certified physician in Pulmonary, Critical Care and board eligible in Allergy and Immunology. Dr. Henig received her B.A. from Yale University and her M.D. from Albert Einstein College of Medicine of Yeshiva University in 1991 with a distinction in immunology. She trained in Internal Medicine at University of California, San Francisco and in Pulmonary/Critical Care and Allergy/Immunology at University of Washington, Seattle.

"I am excited to join Kezar at such an important time in the company’s growth," said Dr. Henig. "Kezar’s scientific excellence in protein homeostasis via protein degradation and secretion presents tremendous opportunity to create elegant therapies for those living with serious and often debilitating diseases. It will be a joy to work alongside Kezar’s talented and dynamic team to realize our full potential by combining science with innovative approaches to development and patient engagement."

CymaBay Therapeutics to Report First Quarter 2020 Financial Results on Monday, May 11

On May 4, 2020 CymaBay Therapeutics, Inc. (NASDAQ: CBAY), a clinical-stage biopharmaceutical company focused on developing therapies for liver and other chronic diseases with high unmet need, reported that it will host a conference call and live audio webcast on Monday, May 11, 2020 at 4:30 p.m. Eastern Time to discuss financial results for the first quarter ended March 31, 2020 and to provide a business update (Press release, CymaBay Therapeutics, MAY 4, 2020, View Source [SID1234557046]).

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Conference Call Details
To access the live conference call, please dial 855-327-6837 from the U.S. and Canada, or 631-891-4304 internationally, Conference ID# 10009543. To access the live and subsequently archived webcast of the conference call, go to the Investors section of the company’s website at View Source

Sangamo Therapeutics Announces First Quarter 2020 Conference Call and Webcast

On May 4, 2020 Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, reported that the Company has scheduled the release of its first quarter 2020 financial results after the market closes on Monday, May 11, 2020 (Press release, Sangamo Therapeutics, MAY 4, 2020, View Source [SID1234557045]). The press release will be followed by a conference call at 5:00 p.m. ET, which will be open to the public via telephone and webcast. During the conference call, the Company will review its financial results and provide a business update.

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The conference call dial-in numbers are (877) 377-7553 for domestic callers and (678) 894-3968 for international callers. The conference ID number for the call is 6043504. Participants may access the live webcast via a link on the Sangamo Therapeutics website in the Investors and Media section under Events and Presentations. A conference call replay will be available for one week following the conference call. The conference call replay numbers for domestic and international callers are (855) 859-2056 and (404) 537-3406, respectively. The conference ID number for the replay is 6043504.

BERGENBIO ASA – PRIVATE PLACEMENT SUCCESSFULLY PLACED

On May 4, 2020 BerGenBio ASA (OSE:BGBIO) ("BerGenBio" or the "Company") reported that contemplated private placement of new shares in the Company (the "Private Placement") (Press release, BerGenBio, MAY 4, 2020, View Source [SID1234556994]).

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The Company is pleased to announce that the Private Placement has been successfully placed, raising gross proceeds of NOK 500 million through the allocation of 13,325,000 shares at a subscription price of NOK 37.50 per share (the "Subscription Price"). The Private Placement, that was oversubscribed, took place through an accelerated book building process after close of market on 4 May 2020. Arctic Securities AS, Carnegie AS and DNB Markets, a part of DNB Bank ASA acted as Joint Bookrunners (together the "Managers") in connection with the Private Placement.

The Company intends to use the net proceeds from the Private Placement to take full advantage of clinical development opportunities stemming from the Company’s technology and to progress readiness for early commercialisation possibilities, as well as for general corporate purposes.

In connection with the Private Placement, a group of employees in the Company realized a small portion of their existing shares or shares acquired through exercise of options, in total 302,500 shares in the Company, at the same price as the subscription price in the Private Placement (the "Secondary Sale", and together with the Private Placement the "Transaction"). The following primary insiders either subscribed for shares or sold shares or options in the Transaction:

Meteva AS, represented on the board of directors by Sveinung Hole, was allocated 1,706,667 shares in the Transaction. Following the Transaction, Meteva will own 21,956,142 shares in the Company, equal to 25.32% of the share capital.

Altitude Capital AS, represented on the board of directors by Grunde Eriksen, was allocated 65,000 shares in the Transaction. Following the Transaction, Altitude Capital AS, will own 780,000 shares in the Company, equal to 0.90% of the share capital.

Richard Godfrey (Chief Executive Officer and primary insider) has through Gnist Holding AS sold 200,000 existing shares in the Company as part of the Transaction. Following the Transaction, Richard Godfrey will own 21,005 shares (equal to 0.02% of the share capital) and 1,542,617 options in the Company.

Endre Kjærland (Associate Director of IP and Contracts and primary insider) will as part of the Transaction exercise options and sell 20,000 shares. Following the Transaction, Endre Kjærland will own 3,262 shares (equal to 0.004% of the share capital) and 130,525 options in the Company.

Gro Gausdal (Director of Research & Bergen Site Leader and primary insider) will as part of the Transaction exercise options and sell 15,000 shares. Following the Transaction, Gro Gausdal will own 143,376 options in the Company.

In addition, non-primary insiders among the Company’s employees will exercise options and sell 67,500 shares as part of the Transaction. The selling employees will enter into a customary 6 months lock-up undertaking on their remaining holdings with the Joint Bookrunners.

The shares allocated in the Transaction will be settled through a delivery versus payment transaction on a regular T+2 basis by delivery of existing and unencumbered shares in the Company that are already listed on the Oslo Stock Exchange pursuant to a share lending agreement between Arctic Securities (on behalf of the Managers), the Company, the sellers in the Secondary Sale and Meteva AS. The shares delivered to the applicants will thus be tradable from allocation. The Managers will settle the share loan with new shares in the Company to be issued by the board of directors of the Company (the "Board") pursuant to an authorization granted at the Company’s annual general meeting held on 16 March 2020. Notification of allocation of shares and payment instructions is expected to be sent to the applicants through a notification from the Managers on 5 May 2020.

Following registration of the new share capital in the Company and issuance of the new shares in the Transaction (including options exercised by employees) with the Norwegian Register of Business Enterprises, which is expected to take place on or about 7 May 2020, the Company will have an issued share capital of NOK 8,672,580.50 divided into 86,725,805 shares, each with a par value of NOK 0.10.

Completion of the Private Placement implies a deviation from the existing shareholders’ pre-emptive rights to subscribe for and be allocated new shares. The Board has considered the Private Placement in light of the equal treatment obligations under under the Norwegian Securities Trading Act and Oslo Børs’ Circular no. 2/2014, and is of the opinion that the proposed Private Placement is in compliance with these requirements. Following careful considerations, the Board is of the view that it will be in the common interest of the Company and its shareholders to raise equity through a Private Placement setting aside the pre-emptive rights of the existing shareholders to subscribe for shares. By structuring the transaction as a Private Placement, the Company will be in a position to raise capital in an efficient manner, with a lower discount to the current trading price and with significantly lower completion risks compared to a rights issue. In addition, the Private Placement was marketed through a publicly announced bookbuilding process.

Subject to inter alia (i) completion of the Private Placement, (ii) relevant corporate resolutions including approval by the Board and the EGM, (iii) prevailing market price of the Company’s shares being noticeably higher than the subscription price, and (iv) approval by the Financial Supervisory Authority of Norway of a prospectus (the "Prospectus"), the Company will carry out a subsequent offering (the "Subsequent Offering") of up to 1,500,000 new shares in the Company. A Subsequent Offering will, if made, and on the basis of the Prospectus, be directed towards eligible shareholders in the Company who (i) are shareholders in the Company as of 4 May 2020, as registered as shareholders in the Company’s register of shareholders with the Norwegian Central Securities Depositary (Nw. Verdipapirsentralen) (the "VPS") as of 6 May 2020, (ii) are not allocated shares in the Private Placement, (iii) are not resident in a jurisdiction where such offering would be unlawful or, for jurisdictions other than Norway, would require any prospectus, filing, registration or similar action, and (iv) have an existing shareholding below a threshold of 150,000 shares in the Company (the "Eligible Shareholders"). The Eligible Shareholders are expected to be granted non-tradable allocation rights. The subscription period in the Subsequent Offering is expected to commence shortly after publication of the Prospectus, and the subscription price in the Subsequent Offering will be the same as in the Private Placement. When deciding the need for and size of a potential subsequent offering, the Board will factor in the amount of upcoming short-term news flow in connection with the Company’s participation in the ACCORD study related to Covid-19 (including the need to avoid that a subsequent offering will provide the Eligible Shareholders with an unreasonable option value). The Board will also consider the trading volume and market price of the shares in the Company in the intermediate period. The Company will issue a separate stock exchange notice with further details on the Subsequent Offering if and when finally resolved.

TargetRx of Shenzhen Raises $21 Million for Novel Small Molecule Cancer Drugs

On May 4, 2020 TargetRx, a Shenzhen company developing small molecules therapeutics for cancer, reported that it has completed a $21.2 million Series A financing, led by CCB Principal Capital Management (Press release, Shenzhen TargetRx, MAY 4, 2020, View Source [SID1234556985]). Founded in 2014, the company is developing novel third/fourth generation candidates with the goal of avoiding acquired drug resistance. Proceeds from the funding will be used for clinical studies of the company’s chronic myeloid leukemia and non-small cell lung cancer treatments and other R&D. The founder of TargetRx, Dr. Yihan Wang, has previously discovered several first-in-class novel drugs.

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