On March 3, 2020 Bracco Diagnostics Inc., the U.S. subsidiary of Bracco Imaging S.p.A., a leading global company in the diagnostic imaging business, reported its commitment to achieve a colorectal cancer screening rate for its employees of at least 80% (Press release, Bracco Diagnostics, MAR 3, 2020, View Source [SID1234555156]).

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Colorectal cancer is a major public health problem. Colorectal cancer is the second leading cause of cancer death, and a cause of considerable suffering among more than 145,000 adults diagnosed with colorectal cancer each year. Colorectal cancer screening can reduce colorectal cancer death rates by both preventing the disease through the detection and removal of precancerous polyps and through detection at early more treatable stages.1

The National Colorectal Cancer Roundtable (NCCRT), established by the American Cancer Society (ACS) and the Centers for Disease Control and Prevention (CDC), has evolved their awareness campaign to increase Colorectal Cancer screening rates implementing the 80% in every community initiative in 2019.2

"Bracco Diagnostics Inc. is committed to the health and wellbeing of our employees, not only by taking the 80% screening rate pledge but also providing market leading products that are used in CT Colonography procedures. CT Colonography, also known as CTC or virtual colonoscopy, is a visual, patient-friendly colorectal screening test that can detect both precancerous and cancerous colorectal abnormalities," said Vittorio Puppo, President and CEO of Bracco Diagnostics Inc. "We have proudly supported for many years the great work of the NCCRT, other patient advocacy organizations and the American College of Radiology Colorectal Cancer Committee. At Bracco Diagnostics we are committed to the effort of eradicating colorectal cancer. Consequently, it is a logical step for Bracco Diagnostics to join the growing number of organizations in New Jersey and across the U.S. that make the 80% In Every Community pledge. I encourage other business leaders to join us in making this pledge for their organizations."

To find a location that performs CT Colonography procedures visit the American College of Radiology CT Colonography center locator at View Source

On March 3, 2020 CNS Pharmaceuticals, Inc. (NASDAQ: CNSP) ("CNS" or the "Company"), a biopharmaceutical company specializing in the development of novel treatments for primary and metastatic cancers of the brain and central nervous system, reported as of February 2020, a patient from the Phase 1 clinical trial for the treatment of glioblastoma multiforme ("GBM"), conducted by Reata Pharmaceuticals, Inc., remains cancer free. GBM is an aggressive type of brain cancer and, currently, there are no effective therapies approved to treat this disease (Press release, CNS Pharmaceuticals, MAR 3, 2020, View Source [SID1234555155]).

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In the Phase 1 trial, 44% of patients experienced a statistically significant improvement in progression-free survival. This 44% disease control rate was based on 11 patients (out of 25 evaluable patients) with stable disease, plus responders. One patient experienced a durable complete response, which is defined by the National Cancer Institute as the disappearance of all signs of cancer in response to treatment. This initial trial was conducted in 2006 and as of February 2020, the patient has remained cancer free for over 13 years.

"We are delighted to provide this update on Berubicin’s potential capabilities given the unmet need for this aggressive disease," commented John M. Climaco, Chief Executive Officer of CNS Pharmaceuticals. "We are looking forward to initiating our Phase 2 clinical trial in the second half of this year with our partner, WPD Pharmaceuticals, Inc. In addition, we expect WPD Pharmaceuticals, Inc. to commence a first-ever Phase 1 trial in children later this year. As previously announced, the pediatric trial will be conducted at Children’s Memorial Health Institute, the largest pediatric hospital in Poland." WPD Pharmaceuticals, Inc. was founded by Dr. Waldemar Priebe, the founder of the Company.

About Berubicin
Berubicin is an anthracycline, a class of anticancer agents that are among the most powerful chemotherapy drugs and effective against more types of cancer than any other class of chemotherapeutic agents. Anthracyclines are designed to utilize natural processes to induce deoxyribonucleic acid (DNA) damage in targeted cancer cells by interfering with the action of topoisomerase II, a critical enzyme enabling cell proliferation. Berubicin treatment of brain cancer patients appeared to demonstrate positive responses that include one durable complete response in a Phase 1 human clinical trial conducted by Reata Pharmaceuticals, Inc.

On March 3, 2020 RhoVac AB ("RhoVac") reported, on 3rd March 2020, that the first patient in Finland has started treatment in the company’s clinical phase IIb study in prostate cancer, a study entitled RhoVac-002 ("BRaVac") (Press release, RhoVac, MAR 3, 2020, View Source [SID1234555154]).

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The first patient in Finland has now started treatment in the clinical study, called BRaVac. This clinical trial phase IIb-study is a randomized, placebo-controlled and double-blind study, with the primary objective of evaluating if treatment with the drug candidate RV001 can prevent or limit the development of advanced prostate cancer after curative treatment. The phase IIb study is an international, multicenter study, which will recruit over 175 patients in six European countries and the US. RhoVac has previously received approval to start phase IIb clinical trials in Denmark, Finland, Belgium, Germany and the US, and is awaiting final approval from the ethical committees in Sweden and the UK. The ambition is that all patients should be recruited by end of Q3 2020. The results report on active treatment part of the study is expected in H2 2021.

On March 3, 2020 China Biologic Products Holdings, Inc. (NASDAQ: CBPO) ("China Biologic" or the "Company"), a leading fully integrated plasma-based biopharmaceutical company in China, reported that the Company plans to release its fourth quarter and fiscal year 2019 financial results on Thursday, March 12, 2020 after the market closes (Press release, China Biologic Products, MAR 3, 2020, View Source [SID1234555153]).

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The Company’s management will hold a conference call at 7:30 a.m. ET on Friday, March 13, 2020, which is 7:30 p.m. Beijing Time on March 13, 2020, to discuss fourth quarter and fiscal year 2019 results. Listeners may access the call by dialing:

US:

1 888 346 8982

International:

1 412 902 4272

Hong Kong:

800 905945

Mainland China:

4001 201203

A telephone replay will be available one hour after the conclusion of the conference call through March 20, 2020. The dial-in details are:

US:

1 877 344 7529

International:

1 412 317 0088

Passcode:

10139946

A live and archived webcast of the conference call will be available through the Company’s investor relations website at View Source

On March 3, 2020 The National Comprehensive Cancer Network (NCCN) Oncology Research Program (ORP) reported three research projects selected to receive funding to improve healthcare provider performance and/or healthcare quality, focusing on enhancing patient care and outcomes for people with advanced non-small cell lung cancer (NSCLC) (Press release, NCCN, MAR 3, 2020, View Source [SID1234555152]). The designated projects will be funded through a collaboration with AstraZeneca, a global, science-led biopharmaceutical company.

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"Lung cancer is still the number one cause of cancer death in the United States," said Wui-Jin Koh, MD, Chief Medical Officer, NCCN. "We’ve seen rapid and robust progress in treating this cancer recently, and it’s having a significant impact on reducing mortality. Now we want to make it easier for medical practices to implement these innovations and make sure they’re reaching every patient who could benefit from them. These projects will hopefully serve as sustainable models for promoting system efficiency and enhancing patient outcomes and satisfaction."

The selected projects are:

Developing a PREcision meDICine Thoracic (PREDICT) Service in a Large Practice Network: Focus on Implementation, Physician and Patient Impact
Debora Bruno, MD, MS, and Navid Sadri, MD, PhD, University Hospitals – Seidman Cancer Center
Randomized Trial of a Supportive Care Mobile Application (App) to Improve Symptoms, Coping, and Quality of Life in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
Joseph Greer, PhD, and Jennifer Temel, MD, Massachusetts General Hospital Cancer Center
System-wide Integration of Plasma-based Next Generation Sequencing into Clinical Pathways for Detection of NCCN Recommended Biomarkers to Improve the Management of Patients with Metastatic Non-squamous NSCLC
Charu Aggarwal, MD, Hospital of the University of Pennsylvania
"AstraZeneca is committed to eliminating cancer as a cause of death," said Adrian Kilcoyne, MD, VP, US Medical Affairs, AstraZeneca. "We cannot do this through innovative medicines alone, we must also be active partners in improving the quality of cancer care for patients. We are pleased to partner with NCCN in support of this important work."

The research projects will begin in the third quarter of 2020 and continue for two years. The results from the funded projects will be disseminated upon completion to improve delivery of cancer care in other practices.

The NCCN ORP fosters innovation and knowledge discovery that improves the lives of people with cancer and supports preclinical, translational, clinical research and quality improvement projects in oncology at NCCN Member Institutions. In an effort to improve collaboration in cancer research, the NCCN ORP also maintains a shared resources website and an informed consent database. For more information, visit NCCN.org/orp.