Arrowhead Pharmaceuticals Announces Proposed Underwritten Offering of Common Stock

On December 2, 2019 Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) reported its intention to offer and sell 4,000,000 shares of its common stock in an underwritten offering pursuant to its existing automatic shelf registration statement (Press release, Arrowhead Pharmaceuticals, DEC 2, 2019, View Source [SID1234551881]). All of the shares in the proposed offering are to be sold by Arrowhead. Arrowhead intends to grant the underwriters a 30-day option to purchase up to an additional 600,000 shares of its common stock. The offering is subject to market conditions, and there can be no assurance as to whether or when the offering may be completed, or the actual size or terms of the offering.

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Goldman Sachs & Co. LLC, Jefferies LLC and Piper Jaffray & Co. are acting as bookrunning managers for the offering, Cantor Fitzgerald & Co. is acting as passive joint bookrunner for the offering and Robert W. Baird & Co. Incorporated and B. Riley FBR, Inc. are acting as co-managers for the offering. Arrowhead intends to use the net proceeds from this offering for general corporate purposes, including working capital, capital expenditures, research and development expenditures and clinical trial expenditures. A portion of the net proceeds may also be used for the acquisition of complementary businesses, products and technologies, or for other strategic purposes.

A shelf registration statement on Form S-3 relating to the public offering of the shares of common stock described above was filed with the Securities and Exchange Commission (the "SEC") and became automatically effective upon filing on December 2, 2019. A preliminary prospectus supplement and accompanying prospectus relating to and describing the terms of the offering will be filed with the SEC and will be available on the SEC’s web site at www.sec.gov. When available, copies of the preliminary prospectus supplement and accompanying prospectus may also be obtained from Goldman Sachs & Co. LLC by mail at 200 West Street, New York, NY 10282, Attention: Prospectus Department, by telephone at (866) 471-2526, or by email at [email protected]; from Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, 2nd Floor, New York, NY 10022, by telephone at (877) 821-7388, or by email at [email protected]; or from Piper Jaffray & Co., Attn: Prospectus Department, 800 Nicollet Mall, J12S03, Minneapolis, MN 55402, by telephone at (800) 747-3924, or by email at [email protected].

Corporate Presentation

On December 2, 2019 NantKwest presented the corporate presentation (Presentation, NantKwest, DEC 2, 2019, https://nantkwest.com/wp-content/uploads/2019/12/NantKwest%20KOL%20December%202019%20Presentation.pdf [SID1234551874]).

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EOC Pharma Raises $71 Million in C Round for China Development of In-Licensed Oncology Drugs

On December 2, 2019 EOC Pharma, the oncology development arm of China in-licensing company Eddingpharm, reported that it raised $71 million in a Series C round led by Tigermed, TF Capital and Yingke PE (Press release, ChinaBio, DEC 2, 2019, View Source [SID1234551857]). Headquartered in Taizhou, EOC manufactures and commercializes oncology products for China use that require mid to late stage clinical development for registration . It currently has a pipeline of six novel products from global biopharmas, including its most recent in-licensing, a Shionogi HER2/EGFR inhibitor intended to treat brain metastasis in advanced metastatic breast cancer patients. Two years ago, EOC completed a $32 million B financing.

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Kleo Pharmaceuticals to Present at Piper Jaffray 31st Annual Healthcare Conference

On December 2, 2019 Kleo Pharmaceuticals, Inc., an immuno-oncology company developing next-generation, fully synthetic bispecific compounds designed to emulate or enhance the activity of biologics, reported that its Chief Executive Officer Doug Manion, MD, will present at the Piper Jaffray 31st Annual Healthcare Conference, to be held December 3-5 at the Lotte New York Palace in New York (Press release, Kleo Pharmaceuticals, DEC 2, 2019, View Source [SID1234551849]).

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During his presentation, Dr. Manion will provide an overview of Kleo’s development strategy for its pipeline of small molecule and synthetic peptide compounds that function similar to highly complex biologics, while offering multiple potential advantages. The overview will also outline Kleo’s key value drivers including its proprietary technology platforms that drive in-house drug development and partnership opportunities, the multiple in-house and collaborative channels through which it is building its immuno-oncology pipeline and its discovery collaboration with PeptiDream. Human studies are anticipated in 2020 for Kleo’s first product candidate to move into the clinic, CD38-ARM, a CD38 targeting antibody recruiting molecule (ARM) to treat multiple myeloma.

Dr. Manion will also discuss another platform technology at Kleo, which uses site-directed, chemical conjugation of off-the-shelf antibodies to enhance or add functionality. Monoclonal antibody therapy enhancers (MATEs) offer a number of opportunities to optimize or repurpose biologics currently in development.

Details of the presentations are as follows:

Event:

31st Annual Piper Jaffray Conference

Date:

December 3

Time:

2:10-2:30 p.m. EST

Location:

Lotte New York Palace, New York

Room:

Harlem Track – Kennedy 2, 4th Floor

CytoSorbents to Present at the Piper Jaffray 31st Annual Healthcare Conference

On December 2, 2019 CytoSorbents Corporation (NASDAQ: CTSO), a critical care immunotherapy leader commercializing its CytoSorb blood purification technology to treat deadly inflammation in critically-ill and cardiac surgery patients around the world, reported that the Company will present an overview of the company at the Piper Jaffray 31st Annual Healthcare Conference on Thursday, December 5, 2019 in New York, NY, and meet with investors in 1×1 meetings throughout the day (Press release, Cytosorbents, DEC 2, 2019, View Source [SID1234551848]).

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Piper Jaffray 31st Annual Healthcare Conference
Where: Lotte New York Palace, 455 Madison Ave, New York, NY
When: Thursday, December 5, 2019 from 11:50AM-12:10PM EST
Webcast: Piper Jaffray 31st Annual Healthcare Conference Webcast Link

A live webcast of the presentation will be available at the above webcast link. An archived replay of the webcast will be available for 90 days following the event.